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Description drugs: Benzylpenicillin novocaine salt (Benzylpenicillinumnovocainum)

Penicillin procaine SALT (Benzylpenicillinumnovocainum).

Procaine salt monohydrate benzilpenitsillinovoy acid.

Synonyms: Abbocillin, Benzylpenicillinum, Biocillin, Duracillin , Novocillin, Novocin, Procaini Benzylpenicillinum, Procillin and others.

The white crystalline powder, odorless, bitter taste. It is soluble in water. Since water forms a thin slurry. Resistant to light. Easily destroyed by the action of acids, alkalis and the enzyme penicillinase.

The spectrum of antimicrobial action does not differ from the sodium and potassium salts of benzylpenicillin.

The theoretical activity of the drug in 1011 ED 1 mg. Practically must contain not less than 970 IU per 1 mg.

The features of the drug is slow absorption and prolonged action when administered intramuscularly.

After a single injection of a suspension, the therapeutic concentration of penicillin in blood stored up to 12 hours.

The drug is only administered intramuscularly. Intravenous and endolyumbalnoe introduction is not allowed.

Enter the 3 - 4 times a day. The average therapeutic doses for adults: single 300,000 IU daily 600,000 units. The highest daily dose for adults 1 200 000 units. Children under the age of 1 year appoint 50 000 - 100 000 IU / kg per day, over 1 year - 50 000 IU / kg per day. The daily dose for adults and children are administered in 1 - 2 admission.

For the administration of the drug are ex tempore suspension: the vial containing the dry salt of procaine penicillin, sterile syringe injected 2 - 4 ml of sterile water for injection or isotonic sodium chloride and sodium vial shaken vigorously; The resulting slurry is quickly drawn into a syringe and injected deep into the muscle of the upper outer quadrant of the buttock. Prior to administration, make sure that the needle does not hit a blood vessel. Thick are injection needle (0.8 mm diameter).

Possible complications and contraindications such as when using SRI other drugs penicillin, as well as increased sensitivity to procaine.

Product: in bottles of 300 000; 600 000 and 1 200 000 units.

Storage: List B. At room temperature.

A mixture of penicillin procaine salt and penicillin sodium salt sootnotenii 3: 1 is produced under the name "Novotsin" (Novocinum) in hermetically-sealed vials containing 400 000 IU (300 000 IU procaine salt, and 100 000 units of sodium penicillin) 800 000 or 1 200 000 units.