Medication Description: Mafenid (Maphenidum)
MAFENID (Maphenidum). 4- (Aminomethyl) -benzenesulfonamide.
Synonyms: Ambamid, Bensulfamidin, Homosulfamidin, Mafenid, Sulfamilon, etc.
Sulfanilamide antibacterial drug for external use. Available in the form of mafenida acetate (synonyms: Sulfamilon acetate, Napaltan, etc.) for the preparation of ointments.
Mafenida acetate has a wide spectrum of action, is effective against gram-positive and gram-negative bacteria and pathogenic anaerobes, the causative agents of gas gangrene. It is not inactivated by para-aminobenzoic acid and does not change the activity in an acidic medium.
Applied for the treatment of infected burns, purulent wounds, pressure sores, trophic ulcers.
Ointment (10%) is applied directly to the affected surface, tampons soaked in ointment are introduced into the cavities, and wipes are also applied to the wounds, smeared with ointment, in a layer of 2 - 3 mm. Usually, 30–70 g of ointment is used per dressing. Before applying the dressing, the wound is cleaned of purulent-necrotic masses. A change of dressings is made daily or 2 - 3 times a week, depending on the amount of purulent discharge. The duration of treatment from 1 to 4 - 5 weeks.
In case of II degree burns, it is possible to apply a dressing once.
When applying the ointment on the burn or wound surface, there may be a burning sensation, pain lasting from 1/2 to 1 to 3 hours; for severe pain, analgesics are prescribed.
The use of the ointment is contraindicated in the presence of a history of toxic-allergic reactions to sulfa drugs.
Product form: 10% ointment (white or white with a yellowish tinge, uniform consistency) in light-protective glass cans of 50 g and 2 kg each.
Storage: List B. In the dark spot.