Description of the medicine: Mafenid (Maphenidum)
MAFENID (Maphenidum). 4- (Aminomethyl) -benzenesulfonamide.
Synonyms: Ambamid, Bensulfamidin, Homosulfamidin, Mafenid, Sulfamilon, etc.
Sulfanilamide antibacterial drug for external use. Available in the form of mafenide acetate (synonyms: sulfamilone acetate, Napaltan, etc.) for the preparation of ointments.
Mafenide acetate has a wide spectrum of action, is effective against gram-positive and gram-negative bacteria and pathogenic anaerobes, pathogens of gas gangrene. It is not inactivated by para-aminobenzoic acid and does not change activity in an acidic environment.
It is used to treat infected burns, purulent wounds, pressure sores, trophic ulcers.
Ointment (10%) is applied directly to the affected surface, tampons impregnated with ointment are introduced into the cavity, napkins lubricated with ointment are also applied to the wounds, a layer of 2 - 3 mm. Typically, 30 - 70 g of ointment is consumed per dressing. Before applying the dressing, the wound is cleaned of purulent-necrotic masses. Bandages are changed daily or 2-3 times a week, depending on the amount of purulent discharge. The duration of treatment is from 1 to 4 - 5 weeks.
With II degree burns, a single dressing is possible.
When applying the ointment to a burn or wound surface, there may be a burning sensation, pain lasting from 1/2 to 1-3 hours; with severe pain, analgesics are prescribed.
The use of ointment is contraindicated if there is a history of toxicological and allergic reactions to sulfonamide drugs.
Release form: 10% ointment (white or white with a yellowish tint, uniform consistency) in cans of light-protective glass of 50 g and 2 kg.
Storage: List B. In the dark place.