Before taking the course, consult a doctor!
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Description of the medicine: Olanzapine (Olanzapine)
Olanzapine.
2-Methyl-4- (4-methyl-1-piperazinyl) -10H-thieno [2,3-b] [1,5] benzodiazepine.
Synonym: Zyprexa, Zyprexa.
By structure and action is close to clozapine (azaleptin). It differs in that the benzodiazepine nucleus contains a methyl-thienyl group instead of a phenyl group.
Has a pronounced antipsychotic effect.
It blocks central dopamine and serotonin receptors.
Quickly and completely absorbed into the digestive tract, C max is 6 h; T1 / 2 - 29-55 h; Is subjected to biotransformation by the kidneys.
Applied in acute forms of schizophrenia and other psychoses, accompanied by positive (delusions, hallucinations, thinking disorders, hostility, etc.) or negative (dull affect, emotional and social isolation, poverty of speech activity, etc.) symptoms. Reduces cognitive and behavioral disorders.
Can be used as an antiemetic.
Assign inside (regardless of time and food intake), starting at a dose of 0.005-0.01 g (5-10 mg) per day (single dose) with a gradual increase to 0.015-0.02 g (15-20 mg) per day .
Possible side effects: drowsiness, extrapyramidal disorders, dizziness, orthostatic hypotension, cholestatic jaundice, dry mouth, constipation, increased appetite, peripheral edema; Increased prolactin levels and liver transaminases.
With violations of the liver, epilepsy, myelosuppression, prostatic hypertrophy, paralytic ileus, children under 18 years of age, it is not recommended to prescribe the drug.
With caution should be used for Parkinson's disease, diabetes, while taking drugs that extend the interval of QT (especially in the elderly).
It aggravates the effect of alcohol and weakens - levodopa.
Product: tablets of 0.005; 0.0075 and 0.01 g (5, 7.5 and 10 mg) (N.28).
Storage: List B.
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