Description of the medicine: Dinezinum (Dinezinum)

DINEZINUM. 10- (2-Diethylaminoethyl) -phenothiazine hydrochloride.

Synonyms: Antipar, Casantin, Deparkin, Diethazini hydrochloridum, Diethazine hydrochloride, Diparcol, Latibon, Parkazin, Thiantan and others.

White crystalline powder. Easily soluble in water and alcohol. In the light, the preparation and its solutions acquire a pink color.

According to its chemical structure, dinesin is close to aminazine and diprazine, partly close to them and by its pharmacological properties. It has a moderate antihistaminic and ganglion-blocking activity. Causes a sedative effect, slightly reduces the basal metabolism. Has a central, mostly n-cholinolytic, effect.

Peripheral holinoliticheskoe action is less pronounced, than at preparations krasavki, tropachina, tsiklodola and other holinoliticheskih antiparkinsonic preparations.

Applied for the treatment of Parkinsonism, Parkinson's disease, torsion dystonia, etc.

Assign inside (after eating) to 0,05 - 0,1 g starting from 1 times and bringing up to 3 - 5 times a day; The daily dose with good tolerability is gradually increased to 1 g.

It is advisable to alternate the use of dinezine with other antiparkinsonian drugs.

Possible side effects: drowsiness, dizziness, adynamia, paresthesia; In rare cases, cutaneous erythematous rash. At the expressed by-effects reduce a dose or cancel a preparation.

When working with the drug, it is necessary to take measures that exclude the ingress of powder and solutions onto the skin and mucous membranes (see Aminazine).

Contraindicated in violations of liver and kidney function, with severe atherosclerosis and cerebral circulation.

Form release: tablets of 0.05 and 0.01 g, coated with a coat of green (Tabulettae Dinezini obductae), in a package of 50 pieces.

Storage: List B. In a dry, sheltered from the world.