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Description medications: trifluperidol (Trifluperidolum)

Trifluperidol (Trifluperidolum). 4- (meta-trifluoromethylphenyl) -1- [3`- (p-fluorobenzoyl) propyl] piperidinol- 4, or 4- [4- (meta-trifluoromethylphenyl) - 4-hydroxypiperidino] 4'-ftorbutirofenon.

Synonyms: Trisedal, Flumoperonum, Psicoperidol, Trifluperidol, Triperidol , Trisedyl.

According to the structure and action close to haloperidol. Characterized by having CF 3 group in the meta position of the phenyl nucleus (from piperidine) in place of the chlorine atom in the para-position of haloperidol.

Strong neuroleptic activity. It enhances the effect of hypnotics, narcotics, analgesics. It has a strong anticonvulsant and antiemetic effect. Strong cataleptic activity. It has no holinoliticheskogo; strong blocking central dopamine receptors.

Trifluperidol is a potent antipsychotic. It quickly reduces the hallucinatory-delirious excitement. By the ability to stop the maniacal excitement is superior to other antipsychotics.

Apply with psychosis, accompanied by motor and mental excitement, especially for the relief of catatonic excitement and gebafrennogo; in protracted periodic attacks of schizophrenia; for conditions involving severe depression and delirium; alcoholic psychosis. In some cases, effective in operation insufficient other neuroleptics. It can also be used as an antiemetic.

Assign inside and intramuscularly.

Inside applied from the dose -0.0005 0.00025 g (0.25 - 0.5 mg) per day, then depending on the effect and tolerability increase the dose of 0.25- 0.5 mg every 2 - 3 days . The daily dose is generally 2 - 6 mg (8 mg). Assign 2 - 4 doses after meals.

Children under 5 years are designated 1/4 and 5 - 15 years 1/2 the adult dose.

In chronic diseases start with intramuscular administration of 1, 25 - 2, 5 mg, then gradually replace the ingestion of the drug injection.

For the relief of acute delusional states is administered intramuscularly at 1, 25 2, 5 mg (sometimes up to 5 mg) once or repeatedly (in the form of a short course).

Possible complications and contraindications are basically the same as with haloperidol.

Method of issuance: pills to 0.0005 g (0.5 mg); 0.1% oral solution in 10 ml vials (1 ml containing 1 mg of the drug); 0.25% solution in 1 mL ampoules.

Storage: List B.