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Description of the medicine: Fotemustin

FOTEMUSTIN (Fotemustin).

(±) -Diethyl- [1- [3- (2-chloroethyl) -3-nitrosoureido] ethyl] phosphonate.

Synonym: Moustoforan, Mustoforan.

The antitumor effect is associated with the alkylation and carbamoylation of the nucleophilic centers of macromolecules in tumor cells.

Applied with melanoma, brain tumors and non-small cell lung cancer.

Assign strictly intravenously at 100 mg / m 2 in the 1, 8 and 15 days every 5-6 weeks, then in the same 1 time in 3 weeks.

Possible side effects: dyspepsia, leuko- and thrombocytopenia, fever, phlebitis.

Contraindications: pregnancy, breast-feeding, children's age.

Form release: powder for injection solutions in bottles of 0.208 g, complete with a solvent.