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Medication Description: Temazepam

TEMAZEPAM (Temazepam).

7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one.

Synonyms: Signopam, Signopam.

White crystalline powder. It is soluble in alcohol, poorly - in water.

Treats preparations of average duration of action.

The drug is quickly and completely absorbed in the gastrointestinal tract, C max is 2 h, T 1/2 - 8-12 h; metabolized in the liver, excreted by the kidneys as inactive metabolites.

Applied as a hypnotic (with violations of sleep), as well as with neurosis, neurasthenia and involutional depression.

Take before bedtime to 0.01-0.02 g (10-20 mg). When used in the usual dose (0.01 mg for adults) there is no pronounced after-effect.

However, the use of the drug may be accompanied by the occurrence of drowsiness, memory impairment, impaired vision, liver and kidney functions, dyspepsia, hematopoietic depression, and allergic reactions.

The drug is contraindicated in myasthenia, disorders of the liver and kidneys, depression, alcohol intoxication, abstructive lung diseases, anemia, pregnancy.

Product form: tablets of 0.01 g (10 mg) (N20).