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Description medications: Fexofenadine (Fexofenadine)

Fexofenadine (Fexofenadine).

4- [1-Hydroxy-4- [4-oksidifenilmetil] -1-piperidinyl] butyl-α, α-dimetilfeniluksusnaya acid.

Available in the form of hydrochloride.

Synonyms: Telfast, Allegra, Telfast.

White or colorless crystalline powder. Slightly soluble in water and chloroform, easily - in ethanol and methanol.

Is a metabolite of terfenadine (see.).

In action very close to that of terfenadine (cm.).

In addition to the blockade of H 1 histamine receptors stabilizes the membranes of fat cells (prevents the release of histamine and other mediators of allergy). It does not possess anticholinergic activity.

It does not have a depressive effect on the central nervous system.

If ingestion is well and rapidly absorbed, with max of 2.8 hours; T S - 14 hours; It stands out mainly with faeces unchanged.

Protivogistaminny effect develops after 1 h after administration, reaching a maximum after 2-3 hours and lasts up to 12 hours.

Applied with allergic rhinitis, hay fever, hives and other allergic diseases.

Assign adults and children aged children and 0.06 g (60 mg) over the age of 12 years 2 times a day.

Side effects (weakness, dizziness, dyspepsia) occur rarely.

Contraindications: age up to 12 years.

Product: pills to 0.12 and 0.18 g (N. 10, 20, 30).

Storage: List B.