Medication Description: Amoxicillin (Amoxicillin)
Synonyms: Amin Amoksikar, Amoksillat, Amokson, Amosin, Amot, Ampireks, Apo-Amoxil, Atoksilin, Gonoform, Gryunamoks, Danemoks, Kuksatsillin, Ospamoks, Ranoksil, Tice, Upsamoks, Flemoksin soljutab, Hikontsil, E-MOX, Amin, Amotid A,--mox, Amoxicar, Amoxil, Amoxillat, Amoxon, Ampirex, Apo-Amoxi, Atoxillin, Cuxacillin, Danemox, Flemoxin solutab, Gonoform, Grunamox, Hiconcil, Ospamox, Polymox, Ranoxil, ff,, ays Gr, Gric, others
Semisynthetic antibiotic of the broad-spectrum penicillin group (see Ampicillin). Active against gram-positive and gram-negative microorganisms. Destroyed by β-lactamases.
Differs in stability in the acidic environment. Effective when ingested.
When ingested quickly and almost completely absorbed, C max is 1-2 hours, T Ѕ - 1-1.5 hours; penetrates into most organs and tissues, accumulates in peritoneal fluid, urine, lungs, intestinal mucosa, gall bladder and bile; partially biotransformed, predominantly excreted by the kidneys.
Applied with infections of the respiratory tract, bile and urinary tract, ENT organs (acute sinusitis and otitis), gastrointestinal tract (including peritonitis, typhoid, cholecystitis), endometritis, infections of the skin and soft tissues, tonsillitis, prostatitis, tick-borne borreliosis , for the prevention of endocarditis and surgical infection, sepsis (in combination with aminoglycosides) and other infectious diseases caused by microorganisms sensitive to penicillins.
Recently, amoxicillin has been used in combination with anti-ulcer drugs (ranitidine, omeprazole, antacid drugs) for gastric and duodenal ulcers associated with Helicobacter pylori infection.
Assign inside adults usually 0.5 g (for severe infections 1 g) 3 times a day; children - at a dose of 0.125-0.25 g 3 times a day, up to 2 years old at a dose of 20 mg / kg in 3 doses.
For the prevention of bacterial endocarditis is used once in a dose of 3 g.
Possible side effects: dyspepsia, insomnia, agitation, dizziness, convulsive reactions, tachycardia, joint pain, interstitial nephritis, dysbacteriosis, candidiasis, allergic reactions, etc.
The drug is contraindicated in allergic diathesis, bronchial asthma, hay fever, infectious mononucleosis, lymphocytic leukemia, gastrointestinal tract history.
Method of production: tablets of 0.125; 0.25; 0.375; 0.5; 0.75 and 1 g (N. 5, 10, 20); capsules of 0.25 and 0.5 g (N. 16, 20); 2.5% and 5% suspension (at 0.125 and 0.25 g in 5 ml) in 60 ml vials; powder and granules for 2.5%; 5% and 8% suspension (syrup).
Storage: List B.
Klonakom-X. Capsules containing 0.25 g of amoxicillin and cloxacillin.