Description of the medicine: Amoxicillin (Amoxicillin)
Synonyms: Amine, Amoxicar, Amoxillate, Amoxon, Amosin, Amotit, Ampirex, Apo-Amoksi, Atoksilin, Gonoform, Grunamoks, Danemoks, Kuksatsillin, Ospamoks, Ranoksil, Taisil, Upsamoks, Flemoksin solutab, Amikotsidmin, Amikotsidmin, Amikotsidmin, Amikotsidmin , A-mox, Amoxicar, Amoxil, Amoxillat, Amoxon, Ampirex, Apo-Amoxi, Atoxillin, Cuxacillin, Danemox, Flemoxin solutab, Gonoform, Grunamox, Hiconcil, Ospamox, Polymox, Ranoxil, Taysil, Troxox, Ufox, Ufox other
Semisynthetic antibiotic of the penicillin group of a wide spectrum of action (see Ampicillin). Active against gram-positive and gram-negative microorganisms. Destroyed by β-lactamases.
It is resistant to acidic conditions. Effective when taken orally.
When administered quickly and almost completely absorbed, C max is 1-2 hours, T Ѕ - 1-1.5 hours; penetrates most organs and tissues, accumulates in the peritonial fluid, urine, lungs, intestinal mucosa, gall bladder and bile; partially subjected to biotransformation, excreted mainly by the kidneys.
Used for infections of the respiratory tract, bile and urinary tract, ENT organs (acute sinusitis and otitis), gastrointestinal tract (including peritonitis, typhoid fever, cholecystitis), endometritis, infections of the skin and soft tissues, tonsillitis, prostatitis, tick-borne borreliosis , for the prevention of endocarditis and surgical infection, sepsis (in combination with aminoglycosides) and other infectious diseases caused by penicillin-sensitive microorganisms.
Recently, amoxicillin has been used in combination with antiulcer drugs (ranitidine, omeprazole, antacid drugs) for gastric and duodenal ulcers associated with Helicobacter pylori infection.
Assign inside adults usually 0.5 g (for severe infections 1 g) 3 times a day; children - at a dose of 0.125-0.25 g 3 times a day, up to 2 years old at a dose of 20 mg / kg in 3 divided doses.
For the prevention of bacterial endocarditis, a single dose of 3 g is used.
Possible side effects: dyspepsia, insomnia, agitation, dizziness, convulsive reactions, tachycardia, joint pain, interstitial nephritis, dysbiosis, candidiasis, allergic reactions, etc.
The drug is contraindicated in allergic diathesis, bronchial asthma, hay fever, infectious mononucleosis, lymphoid leukemia, a history of gastrointestinal tract diseases.
Method of release: tablets of 0.125; 0.25; 0.375; 0.5; 0.75 and 1 g (N. 5, 10, 20); capsules of 0.25 and 0.5 g (N. 16, 20); 2.5% and 5% suspension (0.125 and 0.25 g in 5 ml each) in 60 ml vials; powder and granules for 2.5%; 5% and 8% suspension (syrup).
Storage: List B.
Clonac X. Capsules containing 0.25 g of amoxicillin and cloxacillin.