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Description of the medicine: Intron-A (Intron-A)
INTRON-A (Intron-A).
Recombinant interferon alpha-2b synthesized in E. coli culture.
Has antiviral, immunomodulating and antitumor effect.
Applied with multiple myeloma, Kaposi's sarcoma, hairy cell leukemia and other oncological diseases, as well as chronic hepatitis B, C and D, HIV infection.
Assign usually subcutaneously, intramuscularly, sometimes intravenously, if necessary - intracavitary.
In chronic hepatitis B injected subcutaneously or intramuscularly at 5 000 000 IU daily or 10 000 000 IU 3 times a week for at least 16 weeks.
In chronic hepatitis C, subcutaneously 3,000,000 IU is administered 3 times a week for at least 18 months.
In chronic hepatitis D, subcutaneously injected 5,000,000 IU / m 2 daily or 3 times a week for 3-4 months or more.
In chronic myelogenous leukemia, 4,000,000 to 5,000,000 IU / m 2 per day are prescribed, maintaining doses of 500,000 to 10,000,000 IU / m 2 .
With multiple myeloma, 3,000,000 - 5,000,000 IU are administered 2 times a week during the entire induction therapy period.
With Kaposi's sarcoma, 30,000,000 IU / m 2 daily or 3 times a week are used for HIV infection.
In case of cancer, kidneys are prescribed 20,000,000 IU / m 2 daily for 3 months or more.
In ovarian cancer, 50,000,000 IU of intraperitoneal injection is administered intraperitoneally for 16 weeks.
When malignant melanoma is prescribed intravenously to 20,000,000 IU / m 2 5 times a week from 4 weeks to 2 years.
When bladder cancer is administered intravesical 30 000 000 - 50 000 000 IU once a week for 8-12 weeks.
Solutions are prepared immediately prior to administration.
When using the drug, various side effects are possible: nausea, dizziness, fever, diarrhea, myalgia, arterial hypotension, etc .; At course treatment probably granulotsitopenia, thrombocytopenia, a violation of the liver, stomatitis, etc.
Form release: lyophilized powder for injection solutions in vials of 3,000,000, 5,000,000, 10,000,000 and 30,000,000 IU.
Storage: List B. At temperatures from +2 to +8 ° C.
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