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Description medications: pizotifen (Pizotifen)

Pizotifen (Pizotifen) *. 4- (1-Methyl-4-piperiliden) -9, 10-dihydro-4H-benzo [4, 5] cyclohepta [1, 2-b] thiophene.

Available in the form of the maleate.

Synonyms: Sandomigran, Litec, Pizotylin, Sandolitec, Sandomigran , Sandomigrin, Sanmigran, Sanomigran.

By chemical structure similar to ketotifen (cm.) To partially cyproheptadine (cm.) And amitriptyline (cm.).

It is an antagonist of serotonin (S 1) receptor; It has also protivogistaminnoe and moderate anticholinergic effects.

Applied for the prevention of migraine attacks.

Assign inside usually at a dose of 0.5 mg three times a day. In some cases sufficient dose of 0.5 mg 1 time per day, in other cases it is necessary to increase the dose to 1 mg three times a day.

Pizotifen sometimes more effective than preparations of ergotamine (cm.).

When using pizotifen nausea, drowsiness, fatigue, increased appetite with weight gain. The drug should not be prescribed transport drivers and others whose work requires quick mental and physical reactions.

The drug enhances the effect of tranquilizers, sedatives, tricyclic antidepressants, alcohol. You should not assign pizotifen simultaneously with MAO inhibitors.

The drug is contraindicated in pregnancy, angle-closure glaucoma, difficulty urinating.

Product: tablets containing 0.5 mg (500 mcg) pizotifen (corresponds to 725 mg pizotifen maleate).

Storage: List B.