Description of the medicine: Hydrocortisone acetate (Hydrocortisoni acetas)
HYDROCORTISONE ACETATE (Hydrocortisoni acetas).
Synonyms: Abbocort, Cortibel, Cortoderm, Hydrison, Hydro-Adreson, Synthacort, etc.
White crystalline powder. It is practically insoluble in water.
When administered intramuscularly (in the form of a suspension, it has the same effect and causes the same side effects as cortisone acetate. When applied topically and administered as a suspension into the joint cavity (intrasynovial), it has a strong anti-inflammatory effect without common side effects.
Topically applied in the form of 1% ointment for allergic skin diseases.
Release form: in tubes on 5 g.
For introduction into the joints, a dosage form of a suspension of hydrocortisone acetate 2.5% for injection (Suspensio Hydrocortisoni acetati 2.5% pro injectionibus) is available (in 2 ml ampoules).
It is used for the same purposes and in the same doses as microcrystalline suspension of hydrocortisone.
Shake the suspension before use. The drug after shaking is a suspension of a white or yellowish-white color.
Release form: in ampoules, in a package of 5 ampoules.
Storage: List B. In the dark place.
In eye practice (with conjunctivitis, blepharitis, iritis, iridocyclitis, keratitis, dermatitis of the eyelids, etc.), 0.5% ophthalmic ointment (Unguentum Hydrocortisoni acetatis 0.5%) is used.
The ointment is administered directly from the tube into the conjunctival sac 1-3 times a day, depending on the nature of the disease.
The drug is contraindicated in viral and fungal diseases of the eyes, eye tuberculosis.
In inflammatory diseases of the eye, a suspension of hydrocortisone is also prescribed in the form of eye drops (0.5 - 2.5%), 2 drops in the conjunctival sac 3-4 times a day.
Release form: in tubes of 2, 5 g.
The ointment << Corticomycetin >> (Unguentum <<Corticomycetinum>>) is white with a yellowish tinge. It contains hydrocortisone acetate 0.5 g, chloramphenicol 0.2 g, anhydrous lanolin 10 g, medical vaseline and vaseline oil 22.5 g each, other excipients and distilled water up to 100 g.
They are used for inflammatory and allergic skin diseases, including those complicated by microbial flora sensitive to chloramphenicol (infected and microbial zzzems, neurodermatitis, pyoderma, etc.). The ointment is applied in a thin layer to the affected areas 2 to 3 times a day in a daily dose of 2 to 30 g. When using an occlusive dressing, the drug is prescribed in a reduced dose 1 time per day. The course of treatment usually lasts 7-10 (up to 30) days.
Ointment is contraindicated for tuberculosis, fungal and viral skin diseases, ulcerative skin lesions, wounds, pregnancy. When using the ointment, itching, hyperemia, soreness, exacerbation of acute inflammatory reactions are possible; in these cases, the ointment is canceled.
Release form: in aluminum tubes on 15 g.
Storage: List B. In a cool place.
Hydrocortisone acetate is also part of the emulsion preparation << Fencortisol >> (see Phenyl salicylate) and ointment << Sulfodecortem >> (see Sulfur precipitated).