Bubble skidding

Bubble skidding is a peculiar change in the chorion, expressed in a sharp increase in the size of the villi, during which blister-like extensions are formed. A bubble drift can capture the entire chorion (full bladder drift) or part of it (partial bladder skidding).

Infectious, hormonal, genetic genesis of this disease is supposed. Usually observed in women aged 20-30 years.

Symptoms, course. There is a delay in menstruation for 2-3 months or more, on the background of which there are bloody discharge caused by the rejection of the skip bubbles. Characteristic of the discrepancy between the size of the uterus and the duration of the proposed pregnancy (the size of the uterus exceeds it). The uterus acquires a tauto-elastic consistency. With an increase in the size of the uterus, corresponding to a gestation period of more than 20 weeks, the fetal presence in the uterus can not be established even with the help of electro-, phono- and radiography. In 30-40% of patients there are bilateral teca-luteal cysts of the ovaries, which after the birth of the drift themselves disappear and do not require surgical treatment in these cases. Dangerous subsequent development of chorioepithelioma. Biological and immunological reactions to pregnancy are sharply positive not only with whole, but also with diluted urine due to high titers of chorionic gonadotropin. The diagnosis at the onset of the disease is often erroneous. To clarify the diagnosis, ultrasound is used. Differential diagnosis is performed with spontaneous abortion, multiple pregnancy, polyhydramnios and uterine myoma.

Treatment is the immediate expulsion of a bladder drift from the uterus. For this, scraping of the uterus with a large blunt curette is used, finger removal of the drift with subsequent scraping of the uterus, vacuum aspiration, drug excitation of labor and cesarean section (for large uterus sizes). With pronounced proliferation of chorionic epithelium, cytotoxic drugs are prescribed.

The prognosis is serious. After removing the skid and discharge from the hospital, the patient is carefully observed in the antenatal clinic for 2 years and systematically reacts to the presence of chorionic gonadotropin in the urine (every 3 to 4 months). If a negative reaction becomes positive, the patient is immediately hospitalized to exclude chorionepithelioma.