Charo-Marie's peroneal amyotrophy

Peroneal amyotrophy Charcot-Marie is a hereditary disease manifested by slowly progressing atrophy and weakness of the distal parts of the legs.

Etiology, pathogenesis. The reason is unknown. There is progressive degeneration of the peripheral nerves of the legs, and later of the hands, as well as the roots and anterior horns of the spinal cord.

Symptoms, course. The disease often begins in childhood and adolescence. The first signs are the atrophy of the peroneal muscles with the gradual development of the steppe (cockswalk). Atrophic paresis grows very slowly; In the later stages of the process, brushes are also involved. Tendon reflexes disappear. There is often pain and paresthesia in the legs, as well as light distal hypoesthesia. Coordinator sphere and pelvic functions do not suffer. The composition of the cerebrospinal fluid is normal. Electromyography and study of the speed of carrying out along the nerves testify to the neurogenic genesis of amyotrophy.

The diagnosis is not wasteful: polyneuropathies, even chronic ones, are formed much faster.

Treatment is symptomatic.

Forecast. Even after many years, patients usually retain the ability to move independently.