DISBACTERIOSIS

DISBACTERIOSIS (syn: dysbiosis) - a change in the composition and quantitative ratios of microflora, normally colonizing the hollow organs, communicating with the environment (for example, the upper respiratory tract, intestines), and the human skin. The vital activity of the microflora is associated with the physiological status of the organism and the state of its nonspecific protective forces. Representatives of the so-called normal microflora, usually inhabiting the intestines, upper respiratory tract and human skin, due to the pronounced antagonistic activity protect these organs from the penetration and rapid multiplication of pathogenic and opportunistic microorganisms, perform a number of other functions. These patterns are the most studied in relation to intestinal microflora.

One of the most common causes of dysbiosis is the uncontrolled use of antibacterial drugs, leading to the death of a significant part of the representatives of normal microflora, sensitive to the drug, and the reproduction of a resistant microflora, including pathogenic and opportunistic pathogens. Dysbacteriosis can also be caused by eating disorders, drinking alcohol, severe illnesses, and the like.

With dysbiosis, some representatives of normal microflora (bifidobacteria, lactic acid and intestinal bacillus, etc.) may disappear and rarely occur microorganisms (fungi of the genus Candida, Staphylococcus, Proteus, Pseudomonas aeruginosa, etc.). At the same time, local inflammatory processes are observed to varying degrees, and with a sharp weakening of the body's resistance, a generalized form of endogenous infection, up to sepsis, can develop. Dysbacteriosis is an important link in the pathogenesis of a number of diseases of the digestive system, respiratory tract and skin, affecting the course and outcome of the disease and often requiring special treatment.

Treatment of a dysbacteriosis complex. Biological bacterial preparations, primarily containing bifidobacteria, have a pronounced antagonistic effect against pathogenic and conditionally pathogenic intestinal bacteria, stimulate the formation of local immunity. Showing drugs that increase nonspecific protective forces of the body, antihistamines. When intestinal dysbiosis is prescribed enzyme preparations (panzinorm, festal , etc.). The use of antibiotics is permissible only if certain pathogens prevail in the patient's microflora and a preliminary determination of their sensitivity to antibiotics.

Prevention of dysbiosis is to clarify the unacceptability of unreasonable and uncontrolled use of any antibacterial drugs. In the course of treatment with antibacterial drugs and after it, it is necessary to use bacterial preparations, conduct general restorative therapy and the appointment of adequate nutrition for weakened individuals.