Description of the medicine: Cyclodol (Cyclodolum)
CYCLODOL (Cyclodolum). 1-Phenyl-1-cyclohexyl-3- (N-piperidino) -propanol-1-hydrochloride.
Synonyms: Parkinsan, Parkopan, Romparkin, Anti-Spas, Antitrem, Aparkan, Artane, Benzhexol hydrochoride, Pacitane, Parkan, Parkinsan, Parkopan, Peragit, Pipanol, Romparkin, Tremin, Trihetphenidili hydrochloridum, Trihexyphenidyl hydrochloride, Triphenidyl, Trixyl and others.
White fine crystalline powder. Slightly soluble in water, slowly soluble in alcohol.
Cyclodol is one of the main synthetic anticholinergic drugs used to treat Parkinsonism. It has a strong central n-cholinolytic, as well as peripheral m-cholinolytic action.
In patients with Parkinson's disease, cyclodol, like other anticholinergic drugs, reduces tremor; To a lesser extent affects the rigidity and bradykinesia. In connection with the anticholinergic action of cyclodol, salivation decreases, to a lesser extent, sweating and greasiness of the skin.
Apply cyclidol in Parkinsonism, extrapyramidal disorders caused by neuroleptic drugs, Parkinson's disease, Little's disease, spastic paralysis associated with lesions of the extrapyramidal system; In a number of cases, lowers tone and improves movement in the case of pyramidal character.
Is taken orally (during or after meals) in tablets starting at 0.0005 - 0.001 g (0.5-1 mg) per day; In the subsequent add 1 to 2 mg per day to a daily dose of 0.005 - 0.006 - 0.01 g (5 - 6 - 10 mg) per day (1 - 2 - 3 admission).
Higher doses for adults inside: single 0.01 g, daily 0.02 g.
When applying the drug, there may be side effects associated with its holinolitic properties: dry mouth, discomfort, accommodation, pulse, dizziness. When the dose is reduced or when the drug is withdrawn, the side effects go away.
In case of an overdose, there may be abnormalities in the function of the central nervous system (mental and motor excitement, hallucinatory phenomena, etc.), characteristic of the action of large doses of anticholinergic drugs.
The drug is contraindicated in glaucoma (especially with a closed-angle form), delayed urination, atrial fibrillation.
Caution should be observed with hypertension, severe atherosclerosis, heart disease, liver and kidney problems.
Product: tablets of 0.001; 0.002; 0,005 grams in a package of 50 pieces.
Storage: List A. In a well-ukuporennoy container.