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Description medications: Vigabatrin (Vigabatrin)

Vigabatrin (Vigabatrin).

4-Amino-5-hexenoic acid.

Synonyms: Sabra, Sabril.

The drug has elements of structural similarity with the GABA (see. Aminalon).

It is an irreversible inhibitor of GABA-transferase. When introduced into the body for a long time increases the level of GABA in the central nervous system and acts like a drug valproic acid (see. Atsediprol). It is possible that the mechanism of action of vigabatrin a role also plays a reduction in the central excitatory amino acids (glutamate, aspartate, see lamotrigine.).

Assign an adult inside epilepsy 1-4 grams per day (1-2 admission), children - 40-100 mg / kg.

It contraindicated in renal failure, pregnancy and old age.

Product: pills to 0.5 g (N. 10,100).

Storage: List B.