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Description medication: Quetiapine (Quetiapine)

Quetiapine (Quetiapine).

2- [2- (4-dibenzo [b, f] [1,4] thiazepine-11-yl-1piperazinil) ethoxy] -ethanol fumarate.

Synonym: Seroquel, Seroquel.

Associated 5-HT1-serotonin, dopamine D1- and q2, A-adrenergic and H1 histamine receptors.

Quickly and completely absorbed in the digestive tract, the T1 / 2 of 7 hours; under intense biotransformation, mainly kidneys.

Apply with schizophrenia productive and negative symptoms.

Assign the inside, starting from 0.025 g (25 mg), 2 times a day 1 and increase the dose up to 0.05; 0.1 and 0.15 g - 2.3, respectively during and 4th days; average daily dose of 0.3 grams (300 mg); maximum - 0.75 g (750 mg).

Possible side effects: sleep disorders, anxiety, dry mouth, dyspepsia, tachycardia, orthostatic hypotension, myalgia, oppression blood, increased body temperature, decreased levels of thyroid hormones in the blood, rarely extrapyramidal disorders.

The drug is contraindicated in violation of blood, severe liver and kidney diseases, diabetes, hyperthyroidism, pregnancy, lactation.

Product: pills to 0,025; 0.1, and 0.2 g (25; 100 and 200 mg) (N. 8, 10 and 10 respectively).

Storage: List B.