Before taking the course, consult a doctor!
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Description of the drug: Terfenadine (Terfenadine)
Terfenadine.
Α- (p-tert-Butylphenyl) -4- (hydroxyphenylmethyl) -1-piperidylbutanol.
Synonyms: Bronal, Gistadine, Daylert, Caradonel, Rapid, Reiter, Tamagon, Teldan, Teridin, Terfed, Terfena, Tofrin, Treksil, Bronal, Caradonel, Daylert, Histadine, Rapidal, Riter, Seldane, Tamagon, Teridine, Termenadin, Thelldan, Triludan, Tofrin, Toldan, Trexyl, and others.
White or off-white crystalline powder. Poorly soluble in water, easily - in chloroform, soluble in alcohol.
The blocker of H 1 -gistaminovyh receptors. It has a weak m-hoin-blocking effect.
Does not have a pronounced sedative effect.
When ingestion is well absorbed (about 70%), C max is 1 hour, does not penetrate the blood-brain barrier; Is subjected to intensive biotransformation in the liver with the formation of an active metabolite of fexofenadine (see), is excreted in urine and feces.
The antihistaminic effect develops after 1-2 hours, reaches a maximum after 3-4 hours and continues (after one-time use) for about 12 hours.
Indications for use are the same as for other blockers of H 1 -receptors (allergic rhinitis and conjunctivitis, Quincke's edema, contact dermatitis, dermatoses, allergic reactions when taking drugs, etc.).
Assign inside adults and children over 12 years to 0.06 g (60 mg) 2 times a day or 0.12 g once in the morning; The maximum daily dose of 0.48 g. Children from 6 to 12 years are prescribed to 0.03 g 2 times a day.
When the drug is used in some cases, erythema, galactorrhea, headache, fatigue, dizziness, drowsiness, dryness of the mucous membranes, nausea, vomiting, increased appetite, when the dose is exceeded, ventricular arrhythmias (including tachycardia of the pirouette type).
Contraindications: pregnancy and lactation.
Forms of release: tablets of 0.06 and 0.12 g (60 and 129 mg) (N. 10, 20); 0.6% suspension for oral administration (0.03 g (30 mg) in 1 teaspoonful).
Storage: List B.
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