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Description of the medicine: Pioglitazone (Pioglitazone)


5 - [[4- [2- (5-Ethyl-2-pyridinyl) ethoxy] phenyl] methyl] -2,4-thiazolidinedione hydrochloride.

Synonym: Actos, Actos.

Increases the sensitivity of target tissues to insulin and reduces the yield of glucose from the liver.

Quickly absorbed, C max is 2 h, T S is 3-7 h (in metabolites - 16-24 h); Undergoes biotransformation in the liver with the formation of 2 active metabolites, is excreted primarily with bile.

Apply (in monotherapy or in combination with sulfanilamide drugs, metformin, insulin) in type II diabetes mellitus.

Assign inside (regardless of the time of eating), starting with a dose of 0.015-0.03 g (15-30 mg) 1 time per day, if necessary, increasing it to 0.045 g.

Possible side effects: hypoglycemic reactions, edema, anemia, allergic reactions.

Contraindications: same as repaglinide.

Form release: tablets of 0.015 and 0.03 g (15 and 30 mg).