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Description medications: Ornidazole (Ornidazole)

Ornidazole (Ornidazole).

α- (Chloroethyl) -2-methyl-5-nitroimidazole-1-ethanol.

Synonyms: Avrazor, Tiberal, Avrazor, Tiberal.

The chemical structure similar to that of metronidazole, but contains chloroethyl group in the molecule.

By spectrum antiprotozoal activity of ornidazole is close to metronidazole and tinidazole: acts on Trichomonas, amoeba, giardia, anaerobic bacteria.

It differs from metronidazole longer duration of action and the lack of inhibitory effect on the enzyme atsetaldegidrogenazu and therefore does not lead to accumulation of acetaldehyde and sensibilazatsii organism to action of alcohol (see. Teturam).

If ingestion is rapidly absorbed, bioavailability of 90%, C max - 3 hours, the T ½ - 13 hours; biotransformation in the liver, kidneys predominantly displayed.

Applied for the treatment of trichomoniasis in women and men, as well as amebiasis and giardiasis. You can assign under anaerobic infections.

Is the inside (after eating).

In uncomplicated trichomoniasis adults appoint 0.5 g (1 tablet) in the morning and evening for 5 days or 1.5 g once, in complicated - 0.5 g every 12 hours for 10 days; morning - 25 mg / kg one time a day.

In amoebic dysentery administered for 3 days: adults weighing up to 60 kg and children weighing more than 35 kg - 1.5 g 1 time in the evening; adults with body weight over 60 kg - 1 g in the morning and evening; children weighing up to 35 kg - 40 mg / kg one time a day.

When giardiasis is prescribed for adults and children weighing more than 35 kg, 1.5 g, for children weighing up to 35 to 40 mg / kg, 1 time a day (in the evening) for 5-10 days.

Anaerobic infections dose for adults - 0.5 g every 12 hours.

In applying the drug may dizziness, headache, peripheral neuropathy, tremor, convulsions, impaired coordination of movements and other side effects.

The drug should not be used in I trimester of pregnancy and breastfeeding.

Product: tablets of 0.5 g (N. 6, 10).

Storage: List B.