Description medications: ibuprofen (Ibuprofenum)
IBUPROFEN (Ibuprofenum). d, 1-2- (4-Isobutylphenyl) -propionic acid.
Synonyms: Advil, Bolinet lingval, Bonifen, Bren, Brunifen, Brufen, Burana, Children's Motrin, Deep Relief, Long, Ibupron, Ibusan, Ibutad, Ibuton, Ipren, Markofen, MIG 200, Motrin, Nurofen, profiles, Profinal, Reumafen, Solpafleks, Advil, Algofen, Anflagen, Artofen, Artril, Bonifen, Bren, Brufanic, Brufen, Bufigen, Burana, Children's Motrin, Deef Relief, Dolgit, Ebufac, Iborufen, Ibumetin, Ibuprofen, Ibupron, Ibusan, Ibutad, Ibutop, Inflam, Ipren, Lamidon, Marcofen, MIG 200, Mortifen, Motrin, Napacetin, Nobfen, Nuprin, Norofen, Paxofen, Profen, Profinal, Rebugen, Relcofen, Reumafen, Ruprin, Seclodin, Sendafen, Solpaflex and others.
White or almost white crystalline powder. Practically insoluble in water, easily soluble in organic solvents.
The drug is one of modern NSAIDs. It has anti-inflammatory, analgesic and antipyretic activity moderate.
The mechanism of action of ibuprofen a significant role played by its inhibitory effect on the biosynthesis of prostaglandins.
There is evidence of the stimulating effect of ibuprofen on the formation of endogenous interferon (see. Interferons) and its ability to exert immunomodulatory effects and to improve the rate of non-specific resistance of the organism.
Ibuprofen has rheumatoid arthritis more pronounced effect in the early stages of the inflammatory process with no abrupt changes of the joints. By virtue of it is slightly inferior ortofenu, indomethacin, but it is better tolerated.
Applied for the treatment of rheumatoid arthritis, deforming osteoarthritis, ankylosing spondylitis, and in various forms of articular and extra-articular rheumatic diseases, as well as pain in certain inflammatory lesions of the peripheral nervous system.
Assign into tablets of 0.2 g of 3 - 4 times daily. the dose may be increased to 0.4 g three times a day to achieve a rapid effect. Upon reaching the therapeutic effect of the daily dose is reduced to 0.6 - 0.8 g
It is recommended to first daily dose taken in the morning before eating (for rapid absorption), drinking tea, and the remaining doses - for a day after a meal (for a more gradual absorption).
The drug is generally well tolerated, without causing irritation of the gastric mucosa, which is seen as its main advantage compared to salicylates. In some cases, possible, however, heartburn, nausea, vomiting, flatulence, and allergic skin reactions. When expressed adverse events, reduce the dose or stop receiving the drug.
Ibuprofen is contraindicated in acute ulcer and acute gastric ulcer and duodenal ulcer, ulcerative colitis, increased individual sensitivity to the drug, as well as diseases of the optic nerve.
Caution should be exercised when administering the drug to persons who have suffered in the past peptic ulcer and duodenal ulcer, gastritis, enteritis, colitis, chronic hepatitis, cirrhosis of the liver.
Product: pills to 0.2 g-coated pink, in a package of 30 pieces.
Storage: List B.