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Description medications: Dioksony (Dioxonium)

DIOKSONY (Dioxonium). 1, 2-Bis (4-pirrolidinometil-1 ', 3'-dioxolan-2) ethane diyodmetilat.

Yellowish crystalline powder. It is very easily soluble in water, it is difficult - in alcohol. Aqueous solutions do not change during sterilization.

It is a mixed type of muscle relaxant action. First causes depolarization phase, and then acts as a muscle relaxant antidepolyarizuyuschego.

In the second phase reduces the effect of Neostigmine dioksoniya.

If anesthesia with ether and halothane action dioksoniya increases.

Used for muscle relaxation and off spontaneous breathing, both independently and after pretreatment ditilina.

Enter intravenously. After a preliminary introduction ditilina dioksony used at a dose of 0.03 - 0.04 mg / kg, and for independent use for intubation dioksony administered at a dose of 0.04 - 0.05 mg / kg. Muscle relaxation nastupet after 1, 5 - 3 minutes and lasts for typically 20 - 40 min. If necessary lengthening effect impose an additional 1/2 - 1/3 of the original dose.

Symptoms kurarizatsii can be eliminated (the end of the operation) neostigmine methylsulfate (2 - 4 mg) after pretreatment with atropine.

Apply dioksony only if the conditions for mechanical ventilation.

The drug should be used with caution in infants. In some cases, the drug can cause long-term muscle relaxation.

Broad application dioksony not.

Product: 0.1% solution in ampoules 5 ml (5 mg per vial).

Storage: List A. In the dark spot.