Description of the medicine: Atracurium (Atracurium)
ATRAKURIUM (Atracurium) *.
Synthetic bischetvertichnoe ammonium compound, which has a partial structural similarity with the molecules of tubocurarine and ditiline.
Synonyms: Tracium, Traracrium.
It is a non-depolarizing muscle relaxant. By the nature of the action is close to other drugs of this group. It has a fast, easily reversible muscle-relaxing action. Has low cumulative ability.
After intravenous administration at a dose of 0.5 to 0.6 mg / kg for 90 seconds, there is an opportunity for intubation. At a dose of 0,3 - 0,6 mg / kg causes muscle relaxation lasting 15 - 35 minutes. Additional doses of 0.1 to 0.2 mg / kg prolong relaxation for 15 to 35 minutes. The drug can also be administered as an infusion at a rate of 0.005-0.01 mg / kg per minute.
The action of the drug is removed by the introduction of proserin (with atropine) or other anticholinesterase drugs.
Usually the administration of the drug is well tolerated, there is no change in the cardiovascular system. In connection with the possibility of histamine release, there may be a slight hyperemia of the skin, in rare cases, the phenomena of bronchospasm, anaphylactic reactions.
Contraindications and general precautions are the same as for other nondepolarizing muscle relaxants.
Product: 1% solution (clear pale yellow liquid) in ampoules of 5 and 2, 5 ml (50 and 25 mg).