Description of the medicine: Ammonium chloride (Ammonii chloridum)
AMMONIUM CHLORIDE (Ammonii chloridum).
Synonyms: Ammonium chloride, "Nashatyr", Acidamon, Ammonium schloratum, Amoshlor.
White crystalline, slightly hygroscopic powder odorless; A "cold" salty taste; Volatilized during incandescence. Easily soluble in cold water (1: 3), even easier - in hot (1: 1, 3).
Ammonium chloride has a diuretic effect; However, as an acid-forming agent, ammonium chloride is an effective tool for correcting alkalosis. Easily absorbed from the gastrointestinal tract, the drug is converted into the liver in urea, and during this reaction, HCl: 2NH 4Cl + H 2 CO 3 ~CO (NH 2) 2 + + 2HCl + 2H 2 O is formed. In connection with this, 6 ammonium chloride Use in metabolic alkalosis, including in cases of hypochloraemic alkalosis, the accompanying action of certain diuretics.
Diuretic effect of ammonium chloride is due to the fact that in the process of compensating for acidosis, sodium is mobilized and secreted by the kidneys, which is delayed in the interstitial fluid, and a corresponding amount of water is simultaneously released.
The diuretic effect of ammonium chloride in repeated use is gradually decreasing. After 24 - 48 h, the sodium release due to the compensatory reactions of the body begins to decrease, and after 5 to 7 days the diuretic effect stops; Further administration of the drug does not cause a diuretic effect.
As a diuretic ammonium chloride is sometimes prescribed for edema of cardiac origin.
Take inside (after eating) in the form of 2, 5 - 5% aqueous solution or powder in capsules for 3 to 5 days with a break. The daily dose for adults is 8-12 g (in several doses).
Ammonium chloride also has an expectorant effect and is used for bronchitis, pneumonia, etc. Assign adults to adults for 0.2-0.5 grams, children - 0.1 to 0.25 g per reception 3 to 5 times a day. Take in the form of powder in capsules or 0.5 - 2, 5% solution.
When taking ammonium chloride, stomach irritation, nausea, vomiting may occur. To reduce dyspepsia, the drug should be taken after a meal.
Do not prescribe the drug for acute kidney damage due to the possibility of developing uncompensated acidosis.
Storage: in well-ukuporennyh glass jars in a dry place.
RR: Sol. Ammonii сhloridi 2, 5% 200 ml
DS For 4 tablespoons 5 times a day for 3 to 4 days
RR .: Inf. Rad. Althaeae 6, 0: 180 ml
Ammonii chloridi 3, 0
Sir. Liquiritiae ad 200 ml
M.DS After 3 hours for 1 tablespoon (expectorant)
Rp .: Ammonium chloridi 0.5 (5, 0)
Sir. Liquiritiae 2 mL
Aq. Destill. 100 ml