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Adrenogenital Syndrome


It is characterized by an increased function of the adrenal cortex and an increased content of androgens in the body - male sex hormones that cause adulthood (phenomena of virilization).
Symptolus and current. With the congenital form of the syndrome, the effect of androgens begins during the period of intrauterine development and at birth is manifested by an increase in the clitoris. Sexual maturation in girls begins early (at 6-7 years) and proceeds in a heterosexual type: male secondary sexual characteristics, absence of mammary glands and menstrual function. The acquired form arises from the increased activity of the adrenal cortex or their tumors and is expressed by oligomenorrhea (rare menstruation) or amenorrhea (see Amenorrhea), often infertility, atrophy of the mammary glands, a decrease in the size of the uterus and ovaries, and mild hypertrophy of the clitoris.
Treatment:
Hormonal (cortisone, prednisolone, dexamethasone). Dosage depends on the age of the patient and the severity of the syndrome. With a congenital adrenogenital syndrome, the clitoris is removed and an artificial entrance to the vagina is formed.