Anapyrine

- tablets containing analgin and amidopyrine for 0.25 g. Butadione - for anti-inflammatory reaction is much higher
Amidopyrine and derivatives of salicylic acid, also has analgesic and antipyretic effects. The drug is quickly absorbed and relatively long in the blood. Applied for the treatment of rheumatism in acute form, polyarthritis, gout, erythema nodosum, and so on. Rapidly reduces pain, stops gout attacks, reduces the uric acid in the blood. A good effect is given with iridocyclitis (reduction of exudation and pain), thrombophlebitis of the lower extremities and hemorrhoidal veins (decrease in edema). A single dose of adults - 0.1-0.15 g 4-6 times a day. There may be side effects: nausea, vomiting, pain in the stomach, frequent stools, skin rashes, itching. During the treatment with the drug (it is carried out under close medical supervision) regular blood testing is necessary. To reduce dyspepsia, alkaline-free antacids are prescribed. Allergic reaction, reduction of leukocytes in the blood - indications for drug withdrawal. Butadion is contraindicated in case of peptic ulcer (gastric bleeding is possible), hemopoietic diseases, leukopenia, liver and kidney function, heart rhythm disturbances. When prescribing butadione with other drugs, it is necessary to take into account its ability to delay their excretion from the body by the kidneys (amidopyrine, morphine, penicillin, etc.), thereby contributing to their accumulation in the body and the development of side effects.