Atresia of bile ducts

The developmental flaw in which the bile ducts are completely absent, i.e. Ducts, through which bile enters the gallbladder, and when digestion is released from it. Most often there is a partial absence of bile ducts, or hypoplasia.
Manifestations of the disease are typical. A child is born with jaundice or (with atresia of extrahepatic bile ducts) it develops in the first 3-4 days. Jaundice increases gradually. The stool is discolored from the moment of birth, although its individual portions can be slightly colored. The urine is dark. After 2-3 weeks of life, the sizes of the liver first increase, and then the spleen. In addition, there is also an increase in the abdomen, an expansion of the subcutaneous veins of the abdominal wall. In later stages, in the absence of treatment, increased bleeding, the accumulation of fluid in the abdomen (ascites). If the operation is not performed, the children die 6-9 months later. after birth.
Atresia is distinguished with long-term ongoing physiological jaundice, hemolytic disease of newborns (see below), cytomegalia and toxoplasmosis - intrauterine infection (see below), congenital syphilis, congestion of bile ducts with mucous and bilious corks, congenital hepatitis. With physiological jaundice, the stool is usually redundant due to the allocation of a large amount of thick bile, the urine is dark. The yellowness of the skin tends to decrease, while with atresia it gradually increases.