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Cholagogue preparations


By the mechanism of action, cholagogue funds are usually divided into: drugs that increase the formation of bile in the liver cells, and the means that promote the mechanical advancement of bile in the intestine. The first group includes preparations containing bile acids and bile (dehydrocholic acid, decholin, allochol, cholenzyme), a number of synthetic substances (tsikvalon, nikodin) and herbal preparations whose mechanism of action is to act on the bile formation. The second group of drugs (which contribute to the secretion of bile) include substances that relax the musculature of the biliary tract, for example, atropine, magnesium sulfate and other antispasmodics and anticholinergics. Most of the cholagogues have a combined effect, enhancing the secretion of bile and facilitating its entry into the intestine. Some drugs have both anti-inflammatory (tsikvalon) and antibacterial (nikodin) action.






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