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Choleretic drugs


According to the mechanism of action, choleretic agents are usually divided into: agents that intensify the formation of bile in the liver cells, and agents that promote the mechanical movement of bile into the intestine. The first group includes preparations containing bile acids and bile (dehydrocholic acid, deholin, allohol, cholenzyme), a number of synthetic substances (tsikvalon, nicodin) and drugs of plant origin, the mechanism of action of which consists in the effect on bile formation. The second group of drugs (contributing to the secretion of bile) includes substances that relax the muscles of the biliary tract, for example, atropine, magnesium sulfate and other antispasmodics and anticholinergics. Most choleretic drugs have a combined effect, increasing the secretion of bile and facilitating its entry into the intestine. Some drugs have both anti-inflammatory (cyclone) and antibacterial (nicodin) action.






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