Dermatosis herpetiformis (Duhring's disease)

Refers to a group of chronically occurring disease, the main morphological manifestation of which is the bubble on the skin. It occurs at any age - from breast to the elderly, with the same frequency in both sexes. For children there is a benign course in the majority of the period of puberty usually disappears. The disease is caused by an immunological abnormality associated with increased sensitivity to gluten (grain protein) and a violation of her digestion.
The disease often develops acutely, and further proceeds with chronic bouts of relapse. It is accompanied by general malaise, fever, sudden itching or burning sensation in the area of ​​the lesions. The rash can be on any part of the skin, except the palms and soles. Sometimes mucosal involved in the process.
Skin rash is often symmetrical, inclined to the group. As a result of scratching bubbles and bubbles arise erosion and crust. In their place are then increased pigmentation spots.
It helps with iodine assay, detection of a large number of eosinophils in the bladder and the contents of the peripheral blood, as well as histological and immunofluorescence studies.
Preparations sulfone series (VAT) and its derivatives, and long-term cycles. External treatment is to puncture the bubbles and lubricate the affected areas of alcohol solutions of aniline dyes. On erosion superimposed dressings with antibacterial ointments. In the prevention of relapses is essential diet excluding products of wheat and rye.