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Pemphigus


(Pemphigus of newborns). One of the types of staphylococcal skin lesions that occurs in benign and malignant forms.
A benign form is characterized by the appearance at the end of the first week of life or later against the background of reddening of bubbles and flaccid bubbles measuring 0.20.5 cm filled with a translucent liquid containing pus. Localization - the lower part of the abdomen, arms, legs, inguinal, cervical and other folds of the skin, less often - other parts of the body. All layers of skin are affected. More often abscesses pustules, emptying in groups, but can be and individual.
The general condition is not disturbed, or moderate - lethargy, decreased appetite, the temperature is up to 38 ± C. With early treatment, recovery occurs in 2-3 weeks, although even a benign form of pemphigus can lead to the spread of infection, sepsis.
The malignant form also develops at the end of the first week of life, but with it there are multiple blisters with sizes from 0.5 to 2-3 cm in diameter, the skin between them is sloughing. The temperature is higher than 38 ± С, the condition is severe - in addition to lethargy, lack of appetite, the phenomena of intoxication are expressed - pallor, quickening of the breath, palpitation, vomiting. The disease is highly contagious and, as a rule, ends with sepsis.
Treatment:
Required transfer from the maternity hospital to the department of pathology of newborns in the city hospital. Feeding is natural (mother's milk or donor's milk). Vesicles and blisters are lubricated 23 times a day with alcohol solutions of brilliant green or methylene blue, large formations are pre-pierced with a sterile needle. Local or general ultraviolet irradiation is also shown. Assign antibiotics, drip solutions of albumin, rheopolyglucin, glucose, salt, sometimes antiseptic. At the height of intoxication, antistaphylococcal gamma globulin is administered to maintain immunity and as an antibacterial agent. Transfusions of fresh or frozen plasma, blood products (erythrocyte and leukocyte mass), cardiac glycosides in case of heart failure, diuretics (with intravenous fluids and edema), vitamins (more often group B and vitamin C) are also shown (depending on the manifestations of the disease). ).