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Medication Description: Pentoxyl (Pentoxylum)

PENTOXIL (Pentoxylum). 4-Methyl-5-hydroxymethyluracyl.

White crystalline powder with a faint odor of formalin. Very little soluble in water, practically insoluble in alcohol, soluble in solutions of caustic alkalis.

Like methyluracil, pentoxyl is a pyrimidine derivative and is similar to methyluracil in pharmacological properties.

Applied as a stimulator of leukopoesis with the same indications as methyluracil.

There is evidence of the beneficial effects of pentoxil in patients with trophic ulcers, burns, fistulas, bone fractures, as well as its therapeutic efficacy in gastric ulcer and chronic pancreatitis.

It is also used in patients with infectious and inflammatory diseases of the respiratory system, proceeding with neutropenia and inhibition of phagocytosis.

Assign inside. Duration of treatment is 15 - 20 days and more, depending on the efficacy and tolerability of the drug (in chronic pancreatitis up to 1 - 1, 5 months).

Doses: for adults: 0.2 - 0.3 g (up to 0.4 g) per reception; for children under 1 year old, 0.015 g, from 1 year old to 3 years old — 0.025 g, 3–8 years old — 0.05 g, 8–12 years old, 0.075 g, older than 12 years old — 0.1– 0.15 g per reception. The drug is taken 3 - 4 times a day after meals.

Due to its irritant effect, pentoxyl may, upon ingestion, cause dyspeptic symptoms.

Locally due to the irritating properties of pentoxyl is not used.

Contraindications are the same as for methyluracil.

Method of issuance: powder; tablets, coated, on 0,025 and 0,2 g in pack of 10 pieces.

Storage: List B. In a well-closed container.