Description medications: Azona

Trazodone (Trazodonum) *. 2- {3- [4- (3-chlorophenyl) -1-piperazinyl] -propil-} 1, 2, 4-triazolo [4, 3-a] - pyridine-3 (2H) -one.

Synonyms: Azona, Beneficat, Bimaran, Desyrel , Geripax, Menegan, Molipaxin, Pragmarel, Pragmazine, Sideril, Thombran, Tramensan, Trazolan, Trazone, Tresin, Trittico.

The drug has antidepressant (timolepticheskoe) effect, combined with anxiolytic and tranquilizing effect. By pharmacological properties and neurochemical action is different from the typical antidepressants; does not reduce the depressive effect of reserpine, weakens the central and peripheral effects of amphetamine action of norepinephrine; no appreciable effect on the neuronal uptake of catecholamines, but selectively blocks the reuptake of serotonin.

Apply with different forms of depressions (endogenous, psychotic, neurotic, and Somatogenic al.) With anxiety, tension.

Due to the lack of good tolerability holinoliticheskogo trazodone is widely used in the treatment of elderly patients with organic CNS diseases, as well as in complex treatment of patients with somatic disease, complicated by mental disorders (anxiety, tension, etc.).

Assign inside, intramuscularly and sometimes into a vein. Initial dose ingestion of 50 mg three times a day, then depending on the type and severity of depression to 300 - 500 mg per day. The therapeutic effect is usually observed after 3 - 7 days of starting treatment.

When employed as anxiolytic (somatic and neurotic depression) administered with 25 mg three times a day.

The vein and administered intramuscularly at a dose of 50 mg as anxiolytic premedication before surgery.

Side effects: fatigue, drowsiness, headache, dizziness, insomnia, low blood pressure - are relatively rare and are in dose reduction. The drug should not be administered concurrently with MAO inhibitors.

Method of issuance: capsules containing 25; 50 or 100 mg of drug; 1% solution in ampoules of 5 mL (50 mg per vial).