Description of the medicine: Lactulose (Lactulosum)
Lactulose refers to synthetic disaccharides. When administered orally, it is not absorbed in the gastrointestinal tract. Once in the intestines, it stimulates peristalsis and eliminates constipation.
In addition, by splitting in the colon, it releases hydrogen ions, binds free ammonia, increases the diffusion of ammonia from the blood into the intestines and promotes the release of ammonia from the body.
Lactulose is used in a mixture with galactose and lactose in the form of a syrup for chronic constipation, as well as for hepatic encephalopathy (hepatic coma and precomatous state), in patients with chronic liver diseases.
As a laxative, usually adults are prescribed 1 to 3 tablespoons of syrup per day for 3 days. Then apply maintenance doses of 2 to 5 teaspoons per day. Children are prescribed 1 to 3 teaspoons per day.
For liver diseases, adults take 2 to 3 tablespoons 3 times a day.
When using the drug, nausea, flatulence, diarrhea are possible. In these cases, reduce the dose.
The drug is contraindicated in diabetes.
Release form: in bottles of 500 ml containing in 100 ml 67 g of lactulose, about 11 g of galactose and 6 g of lactose, in the form of a syrup called "Portalak" (Portalak) *.
A similar drug, manufactured under the name "Normase" (Normase, Italy), is recommended for adults with constipation of 7 ml in the morning and evening before meals; with liver diseases - from 15 to 45 ml (1-3 tablespoons) 3 times a day. Children are prescribed 0.5-1.0 ml per 1 kg of body weight (in the morning).