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Description of the medicine: Sodium thiosulfate (Natrii thiosulfas)
Sodium thiosulphate (Natrii thiosulfas) (See also Magnesium sulfate).
Synonyms: Sodium hyposulfite, Natrium hyposulfurosum, Natrium thiosulfuricum.
Colorless transparent crystals are odorless, salty-bitter in taste. Very easily soluble in water (1: 1), almost insoluble in alcohol. At a temperature of about + 50 ° C, it melts in crystallization water.
The aqueous solution (30%, pH 7, 8 - 8, 4) is sterilized at a temperature of + 100 ° C for 30 minutes (20 g of sodium bicarbonate are added to 1 liter of the solution).
Sodium thiosulfate has a counter-toxic, anti-inflammatory and desensitizing effect.
As a counter-toxic agent used for poisoning with compounds of arsenic, mercury, lead (non-toxic sulphites are formed), hydrocyanic acid and its salts (less poisonous rhodanous compounds are formed), iodine, bromine salts.
Enter intravenously for 5 - 10 ml of 30% solution, with lesions cyanide compounds - 50 ml of 30% solution. Inside appoint 2 to 3 g per reception as a 10% solution in water or in an isotonic solution of sodium chloride.
Assign also intravenously and orally for allergic diseases, arthritis, neuralgia.
External applied for the treatment of patients with scabies (see also Benzilbenzoate) by the method of Demjanovich, based on the ability of sodium thiosulfate to decompose in an acidic medium, releasing sulfur and sulfur dioxide, which have an antiparasitic effect. A 60% solution of sodium thiosulfate is rubbed into the skin (successively for 2-3 minutes in the left and right upper limbs, trunk, left and right lower limbs, only for 10-15 minutes). After the end of rubbing, take a break for a few minutes until the skin dries and the crystals appear on it. Then the second cycle of rubbing is carried out in the same sequence. After drying the skin, rub a 6% solution of hydrochloric acid, pouring it on the palm, in the same order 3 to 4 times for 10-15 minutes with interruptions until the solution dries on the skin after each rub. Washing is allowed after 3 days.
Form release: powder; 30% solution in ampoules of 5; 10 and 50 ml.
Rr .: Natrii thiosulfatis 10.0
Aq. Destill. 100 ml
M.DS Inside for 1 - 2 tablespoons in 5 to 10 minutes
RR: Sol. Natrii thiosulfatis 30% 5 ml
DtdN 6 in ampull.
S. 5 ml per vein.
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