Medication Description: Cefalexin (Cefalexinum)
Cefalexinum. 7 (D-a-Aminophenyl-acetamido) -3-methyl-3-cephem-4-carboxylic acid monohydrate.
Synonyms: Tseporex, Baclodin, Basporin, Brisoral, Cefabiot, Cefalival, Cefaxin, Cefaxin, Cefibacter, Ceflon, Cephalexine, Ceporex, Efalexin, Esporin, Kefexin, Keflex, Keforal, Larixin, and my, my, my, my, my, my, my, or my, Sencephalin, Sepexin, Septilisin, Sintolexyn, Sporol, Talinsul, Torlasporin, Totaceprin, Ultralexine, Vapocilin, etc.
White or white with a slightly yellowish tinge powder with a characteristic odor. It is difficult and slowly soluble in water, practically insoluble in alcohol.
Cefalexin is a first-generation cephalosporin antibiotic used internally. The drug is stable in an acidic environment; when ingested quickly (within 1, 5 - 2 hours) and almost completely absorbed when used on an empty stomach and somewhat slower - when taken after a meal. Therapeutic concentration in the blood after a single dose is maintained for 4 to 6 hours. It is excreted in significant quantities in the urine in unchanged form. A small part is excreted in the bile. Bad penetrates the blood-brain barrier.
Assign with inflammatory processes of different localization; acute and chronic pyelonephritis, cystitis, prostatitis, infections of the upper respiratory tract (tonsillitis, pharyngitis), pneumonia, bronchopneumonia, pleural empyema and lung abscess et al., otitis, sinusitis, tonsillitis, skin and soft tissue infections (abrasions, abscesses, pyoderma , lymphangitis, etc.), acute and chronic osteomyelitis, gonorrhea, and other diseases caused by microorganisms sensitive to the drug.
Cefalexin is administered orally, regardless of the meal.
Accepted in the form of capsules, tablets and suspensions.
A single dose for adults is 0.25 - 0.5 g, daily 1 - 2 g. Children are prescribed at the rate of 25 - 50 mg / kg per day. In severe infections, the dose for adults can be increased to 4 g per day (maximum), for children - up to 100 mg / kg. The daily dose is divided into 4 doses. The duration of treatment is usually 7 to 14 days.
In case of violation of the excretory function of the kidneys, the dose is reduced (due to the danger of cumulation).
To prepare the suspension, 80 ml of distilled water is added to a vial containing 2, 5 g of the substance, before dispensing from the pharmacy, and shaken. 1 ml of the finished suspension contains 25 mg of cefalexin. The suspension is dosed with a special spoon, on which there are two labels: the lower one corresponds to 2, 5 ml (62, 5 mg), the upper one - 5 ml (125 mg).
With drug treatment, nausea, abdominal pain and diarrhea are rare; allergic reactions are possible. With prolonged treatment, reversible neutropenia is possible. Dysbacteriosis and superinfection (candidiasis) may occur.
Urine in patients taking cephalexin may give a false positive reaction for glucose.
Contraindications to use are the same as for other cephalosporins.
Form release: in capsules of 0.25 g; tablets of 0.5 g; powder for suspensions of 2, 5 g (Рulvis Serhalahini 2, 5 pro suspension) in bottles.
Storage: List B. In a dry, dark place at room temperature. The aqueous suspension is stored at room temperature for not more than 6 days or in the refrigerator for no more than 14 days.