Description of the medicine: Cefuroxime (Cefuroxim)
Cephalosporin antibiotic of the second generation.
Synonyms: Ketotsef, Altacef, Cefamar, Cefogen, Cefoprim, Cefurex, Cefurin, Gibicef, Ipacef, Itorex, Kefurox, Lafurex, Spectrazol, Ultroxim, Zenacef, Zinacef and others.
Available in the form of sodium salt.
When ingestion is almost not absorbed. It is used intravenously and intramuscularly. Has a wide spectrum of antimicrobial activity and more than other cephalosporins is effective against staphylococci, including b-lactamase-forming strains. It is also effective against b-lactamase-forming gonococci.
Applied for various infectious diseases, including infections of the respiratory and urinary tract, bones, joints, etc.
Introduce adults intramuscularly and intravenously by 0.75 g 3 - 4 times a day in the presence of gram-positive pathogens and 1, 5 g 3 - 4 times a day in the presence of gram-negative pathogens. Children are administered at the rate of 50 100 mg / kg per day (in 3 - 4 injections).
Possible side effects and contraindications are the same as for other antibiotics of the cephalosporin series.
Product: in bottles of 0.75 g.
Storage: List B. In the dark place at a temperature of no higher than +25 "C.
Abroad, a cefuroxime derivative is produced - cefuroxime axetil (Sefurochime ahetil), a drug intended for oral administration.
Synonyms: Makhitil, Zinnat.
Replacement of the carboxy group by a more complex ester radical allowed to obtain a compound that is stable in the acidic contents of the stomach and decomposes in the intestine with the release of active cefuroxime.
The drug is effective for various infectious diseases caused by susceptible to cefuroxime strains of microorganisms.
Assign inside adults to 0.25-0.5 g 2 times a day (at intervals of 12 hours), children older than 5 years - 0,125 - 0,25 g 2 times a day.