Medication Description: Cefuroxime (Cefuroxim)
Second-generation cephalosporin antibiotic.
Synonyms: Ketocef, Altacef, Cefamar, Cefogen, Cefoprim, Cefurex, Cefurin, Gibicef, Ipacef, Itorex, Kefurox, Lafurex, Spectrazol, Ultroxim, Zenacef, Zinacef, etc.
Available in sodium salt form.
When ingestion is practically not absorbed. It is used intravenously and intramuscularly. It has a wide spectrum of antimicrobial action and more than other cephalosporins are effective against staphylococci, including β-lactamase-forming strains. Effective also against b-lactamase-forming gonococci.
Applied with various infectious diseases, including infections of the respiratory and urinary tract, bones, joints, etc.
Adults are injected intramuscularly and intravenously at 0.75 g 3–4 times a day with gram-positive pathogens and 1, 5 g 3–4 times a day with gram-negative pathogens. Children are administered at the rate of 50–100 mg / kg per day (in 3–4 injections).
Possible side effects and contraindications are the same as for other cephalosporin antibiotics.
Form release: in bottles of 0.75 g.
Storage: List B. In the dark place at a temperature not higher than + 25 "C.
A derivative of cefuroxime, cefuroxime axetil (Céfurochime Achetil), a drug intended for oral administration, is produced abroad.
Synonyms: Mahitil, Zinnat.
Replacing the carboxy group with a more complex ester radical made it possible to obtain a compound that is stable in the acidic contents of the stomach and decomposes in the intestine with the release of active cefuroxime.
The drug is effective in various infectious diseases caused by strains of microorganisms that are sensitive to cefuroxime.
Assign inside for adults at 0.25 - 0.5 g, 2 times a day (with an interval of 12 hours), for children over 5 years old - at 0.125 - 0.25 g, 2 times a day.