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Description of the medicine: Cefuroxim (Cefuroxim)

CEFUROKSIM (Cefuroxim) *.

Cephalosporin second-generation antibiotic.

Synonyms: Ketocef, Altacef, Cefamar, Cefogen, Cefoprim, Cefurex, Cefurin, Gibicef, Ipacef, Itorex, Kefurox, Lafurex, Spectrazol, Ultroxim, Zenacef, Zinacef, etc.

Available in the form of sodium salt.

When ingested, it is practically not absorbed. It is used intravenously and intramuscularly. It has a wide spectrum of antimicrobial activity and more than other cephalosporins it is effective against staphylococci, including b-lactamase-forming strains. It is also effective against b-lactamase-forming gonococci.

It is used for various infectious diseases, including infections of the respiratory and urinary tracts, bones, joints, etc.

It is administered to adults intramuscularly and intravenously 0.75 g 3-4 times a day in the presence of gram-positive pathogens and 1.5 g 3-4 times a day in the presence of gram-negative pathogens. Children are administered at a rate of 50 to 100 mg / kg per day (in 3-4 doses).

Possible side effects and contraindications are the same as for other cephalosporin antibiotics.

Release form: in bottles on 0,75 g.

Storage: List B. In the dark place at a temperature of no higher than + 25 "C.

A cefuroxime derivative is produced abroad - cefuroxime axetil (Cefuroxime achetil) - a drug intended for oral administration.

Synonyms: Machitil, Zinnat.

Replacing the carboxy group with a more complex ether radical made it possible to obtain a compound stable in the acidic contents of the stomach and decomposing in the intestine with the release of active cefuroxime.

The drug is effective in various infectious diseases caused by microorganism strains sensitive to cefuroxime.

Assign inside adults at 0.25 - 0.5 g 2 times a day (with an interval of 12 hours), for children over 5 years old - at 0.125 - 0.25 g 2 times a day.