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Description of the medicine: Piracetam (Pyracetamum)

PIRACETAM (Pyracetamum). 2-oxo-1-pyrrolidinylacetamide.

Synonyms: Nootrotil, Pyramme, Apagan, Breinox, Cerebropan, Ceretran, Ciclocetam, Cintilan, Dinacel, Dinagen, Encefalux, Eumental, Euvifor, Fortineural, Gabacet, Gericetam, Merapiran, Neutrofin, Noocebril, Noroo, Noroof, Noroo, Noroo, Noroo, Noroo, Noroo, Noroo, Noroo, Noroo, Noroo Piramem, Piratam, Pirroxil, Pyramem, Stimubral, Stimocartex, etc.

White or almost white crystalline powder. Easily soluble in water, soluble in alcohol; pH of aqueous solutions 5, 0 - 7, 0.

Piracetam is the main representative of the group of nootropic drugs. At present, a number of its direct analogues and homologues (ethiracetam, oxyiracetam, etc.) similar to it in action have been synthesized, however, piracetam continues to be the main drug of this group.

Piracetam is well absorbed when taken orally. When introduced into the body, it penetrates into various organs and tissues, including brain tissue. Virtually not metabolized. It is excreted by the kidneys.

Piracetam has a positive effect on metabolic processes and blood circulation of the brain. Stimulates redox processes, enhances glucose utilization, improves regional blood flow in ischemic areas of the brain. The drug increases the energy potential of the body by accelerating the turnover of ATP, increasing the activity of adenylate cyclase and inhibiting the nucleotide phosphatase. Improving energy processes under the influence of piracetam leads to an increase in the stability of brain tissue during hypoxia and toxic effects. There is evidence of an increase in the synthesis of nuclear RNA in the brain under the influence of piracetam.

The drug is very toxic (in acute experiments on animals, the lethal dose exceeds 10 g / kg when injected into a vein).

The healing properties of piracetam are determined by its ability to improve the integrative activity of the brain, promote memory consolidation, improve learning processes, restore and stabilize impaired brain functions.

Piracetam is used in adults and children for various diseases of the nervous system, especially associated with vascular disorders and pathology of the metabolic processes of the brain, including in the elderly and senile.

In neurological practice, it is prescribed for cerebral atherosclerosis, vascular parkinsonism and other diseases with the phenomena of chronic cerebrovascular insufficiency, manifested in impaired memory, attention, speech, dizziness, etc., as well as changes in cerebral circulation, with coma and subcomatous conditions after brain injuries and intoxications, as well as during rehabilitation after such conditions. Piracetam is also used for diseases of the nervous system, accompanied by a decrease in intellectualnesthetic functions and disorders of the emotional-volitional sphere.