Medication Description: Tetracycline (Tetracyclinum)
Synonyms: Deschlorbiomycin, Achromycin, Cyclomycine, Deschloraureomycin, Hostacyclin, Panmycin, Polycicline, Steclin, Tetrabon, Tetracyn, etc.
Yellow crystalline powder; odorless, bitter in taste. Very little is soluble in water, it is difficult - in alcohol. It is steady in subacidic environment, easily collapses in solutions of strong acids and alkalis. When stored in the light darkens. Hygroscopic. It has the ability to luminesce under the action of blue-violet rays.
Tetracycline is an antimicrobial agent produced by Streptomyces aurefaciens or other related organisms.
Apply tetracycline inside and out. A patient is prescribed for patients with pneumonia, bronchitis, purulent pleurisy, subacute septic endocarditis, bacterial and amoebic dysentery, whooping cough, sore throat, scarlet fever, gonorrhea, brucellosis, tularemia, typhus, and recurrent typhus, psittacosis, and infectious diseases. with other infectious diseases caused by microorganisms sensitive to this antibiotic. Tetracycline can also be used to prevent infectious complications in surgical patients. Topically prescribed tetracycline for infectious diseases of the eye, burns, phlegmon, mastitis, etc.
There is evidence of significant efficacy of tetracycline for cholera.
Tetracycline and other drugs in this range are used to treat gonorrhea.
In severe septic diseases, tetracycline can be used with other antibiotics.
Assign inside (tablets) during or immediately after a meal.
Dose for adults 0.2 - 0.25 g 3 - 4 times a day (washed down with water). Children older than 8 years of age are prescribed in a daily dose of 20-25 mg / kg. Prescribing the drug to adults at doses of less than 0.8 g per day should not be, because, in addition to insufficient therapeutic effect, the development of resistant forms of microorganisms is possible.
In severe cases of the disease, it is more expedient to start with parenteral administration of drugs of the tetracycline group - tetracycline hydrochloride or oxytetracycline hydrochloride.
The course of treatment is on average 5-7 days. After the disappearance of the symptoms of the disease, the drug continues to take for 1 to 3 days.
Tetracycline is usually well tolerated, however, like other antibiotics with a broad spectrum of antibacterial action, can cause side effects: loss of appetite, nausea, vomiting, intestinal dysfunction (mild or severe diarrhea), changes in the mucous membranes of the mouth and the gastrointestinal tract ( glossitis, stomatitis, gastritis, proctitis); allergic skin reactions, angioedema, etc. may occur.
Tetracycline and other drugs in this range can increase the sensitivity of the skin to the action of sunlight (photosensitization).