Description of the medicine: Tetracycline (Tetracyclinum)
Synonyms: Deschlorbiomycin, Achromycin, Cyclomycine, Deschloraureomycin, Hostacyclin, Panmycin, Polycicline, Steclin, Tetrabon, Tetracyn, etc.
Flavourless yellow crystalline powder, bitter taste. It is very slightly soluble in water, it is difficult in alcohol. It is stable in a slightly acidic environment, it is easily destroyed in solutions of strong acids and alkalis. It is dark when stored in the light. Hygroscopic. It has the ability to luminesce under the influence of blue-violet rays.
Tetracycline is an antimicrobial substance produced by Streptomyces aurefaciens or other related organisms.
Tetracycline is used orally and externally. Inside, it is prescribed for patients with pneumonia, bronchitis, purulent pleurisy, subacute septic endocarditis, bacterial and amoebic dysentery, whooping cough, tonsillitis, scarlet fever, gonorrhea, brucellosis, tularemia, typhus and relapsing fever, psittacosis, with infectious diseases of the urinary tract, urinary tract infections, urinary tract infections, with other infectious diseases caused by microorganisms sensitive to this antibiotic. Tetracycline can also be used to prevent infectious complications in surgical patients. Tetracycline is prescribed locally for infectious diseases of the eyes, burns, phlegmon, mastitis, etc.
There is evidence of significant tetracycline efficacy in cholera.
Tetracycline and other drugs of this series are used to treat gonorrhea.
In severe septic diseases, tetracycline can be used with other antibiotics.
Assign inside (in tablets) during or immediately after a meal.
The dose for adults is 0.2 - 0.25 g 3-4 times a day (washed down with water). Children over 8 years of age are prescribed in a daily dose of 20 - 25 mg / kg. Prescribing the drug to adults in doses of less than 0.8 g per day should not be, since, in addition to the insufficient therapeutic effect, the development of stable forms of microorganisms is possible.
In severe cases of the disease, it is advisable to start with parenteral administration of drugs of the tetracycline group - tetracycline hydrochloride or oxytetracycline hydrochloride.
The course of treatment averages 5 to 7 days. After the disappearance of the symptoms of the disease, the drug continues to be taken for 1 to 3 days.
Tetracycline is usually well tolerated, however, like other antibiotics with a wide spectrum of antibacterial effects, it can cause side effects: decreased appetite, nausea, vomiting, impaired bowel function (mild or severe diarrhea), changes in the mucous membranes of the mouth and gastrointestinal tract ( glossitis, stomatitis, gastritis, proctitis); allergic skin reactions, Quincke's edema, etc. may occur.
Tetracycline and other drugs of this series can increase the sensitivity of the skin to the action of sunlight (photosensitivity).