Medication description: Levomycetin soluble succinate (Laevomycetini succinas solubile)
LEVOMICETINA SUCCINATE SOLUBLE (Laevomycetini succinas solubile).
D- (-) -treo - 1 - pair - Nitrophenyl-2-dichloroacetylamino-propanediol - 1, 33 - sodium succinate.
Synonym: Chlorocide C.
Dry porous mass of white or white with a yellowish tinge, with a slight specific smell, bitter in taste. Very easily soluble in water, a little - in alcohol. Hygroscopic: pH 30% aqueous solution 6, 4 - 7, 5.
According to the antibacterial spectrum of chloramphenicol, sodium succinate (soluble chloramphenicol succinate) does not differ from levomycetin, but as a drug, soluble in water, can be used for injection.
It is prescribed for typhoid and paratyphoid, dysentery, brucellosis, whooping cough, pneumonia of various etiologies, purulent infections and other infectious diseases. Also used for the prevention and relief of infections with wound eye damage.
For common infections, they are injected subcutaneously, intramuscularly or intravenously.
Dose for adults 0.5 - 1, 0 g (in the form of a 20% solution) per injection 2 - 3 times a day (at intervals of 12 - 8 hours). If necessary, the daily dose is increased to 4 g.
Children are recommended to be administered intramuscularly: the daily dose for children under 1 year is 25–30 mg / kg, older than 1 year — 50 mg / kg (in 2 doses with an interval of 12 hours).
In ophthalmic practice is used in the form of parabulbar injections and installations. Enter parabulbarny 0,2 - 0,3 ml of 20% solution 1 - 2 times a day. In the conjunctival sac instilled 5% solution of 1 - 2 drops 3 - 5 times a day.
Possible side effects and contraindications are the same as for chloramphenicol.
Product: in bottles of 0.5 and 1 g (based on chloramphenicol).
Storage: List B. In a dry, dark place at a temperature not higher than +20 C.
Solutions for injections are prepared on a 0.25 - 0.5% solution of novocaine, for installations - on sterile water for injections.