Description of the medicine: Chloramphenicol soluble succinate (Laevomycetini succinas solubile)
Levomycetin soluble succinate (Laevomycetini succinas solubile).
D- (-) -treo - 1 - pair - Nitrophenyl-2-dichloroacetylamino-propanediol - 1, 33 - sodium succinate.
Synonym: Chlorocide S.
Dry porous mass of white or white with a yellowish tinge of color, with a faint specific smell, bitter taste. It is very soluble in water, little in alcohol. Hygroscopic: pH of a 30% aqueous solution of 6, 4 - 7, 5.
According to the antibacterial spectrum of chloramphenicol, sodium succinate (soluble chloramphenicol succinate) does not differ from chloramphenicol, but as a drug soluble in water, it can be used for injection.
It is prescribed for typhoid and paratyphoid fever, dysentery, brucellosis, whooping cough, pneumonia of various etiologies, purulent infections and other infectious diseases. Also used for the prevention and relief of infections with wound damage to the eyes.
In general infections, they are administered subcutaneously, intramuscularly or intravenously.
The adult dose is 0.5-1.0 g (in the form of a 20% solution) per injection 2-3 times a day (at intervals of 12-8 hours). If necessary, increase the daily dose to 4 g.
Children are recommended to enter intramuscularly: the daily dose for children under 1 year of age is 25-30 mg / kg, older than 1 year - 50 mg / kg (in 2 doses with an interval of 12 hours).
In ophthalmic practice, they are used in the form of parabulbar injections and installations. 0.2 - 0.3 ml of a 20% solution is administered parabulbarno 1-2 times a day. A 5% solution is instilled into the conjunctival sac, 1 to 2 drops 3-5 times a day.
Possible side effects and contraindications are the same as for chloramphenicol.
Release form: in bottles of 0.5 and 1 g (based on chloramphenicol).
Storage: List B. In a dry, dark place at a temperature of no higher than +20 C.
Injection solutions are prepared on 0.25 - 0.5% novocaine solution, for installations - on sterile water for injection.