Medication Description: Streptocid (Streptocidum)
Synonyms: White Streptocide, Ambesid, Deseptyl, Dipron, Prontalbin, Prontalin, Prontoin, Prontosil album, Streptamin, Streptocidum album, Streptozol, Sulfamidyl, Sulfanilamide, Sulfanilamidum, Sulphanilamide, etc.
White crystalline powder; odorless. It is slightly soluble in water (1: 170), lightly - in boiling water, it is difficult - in alcohol (1:35), soluble in solutions of caustic alkalis.
It has an antimicrobial effect on streptococci, meningococci, gonococci, pneumococci, Escherichia coli and some other bacteria.
With the introduction of streptotsid quickly absorbed. The highest concentration of the drug in the blood is created within 1 to 2 hours after ingestion. After 4 h, it is found in the cerebrospinal fluid. It is allocated mainly (90 - 95%) kidneys.
Streptocid is used to treat angina, erysipelas, cystitis, pyelitis, enterocolitis, for the prevention and treatment of wound infections and other infectious diseases.
Assign inside adults for 0.5 - 1, 0 g 5 - 6 times a day, all in a day 3 - 6 g; children under 1 year old - at 0.05 - 0.1 g per reception from 2 to 5 years old - 0.2 - 0.3 g each, from 6 to 12 years old - at 0.3 - 0.5 g In case of unconsciousness and vomiting, it is possible to replace the administration of the drug by injecting it into a muscle, under the skin or into a vein of a soluble streptocide.
Higher doses for adults inside: single 2 g daily 7 g.
With superficial infectious diseases of the skin and mucous membranes of the nose and ear, with burns, ulcers, etc. Streptocid is used as an ointment (10%) or liniment (5%). For deep wounds, streptocide is introduced into the wound cavity in the form of thoroughly ground sterilized powder (5 - 10 - 15 g); at the same time appoint sulfanilamide (or other antibacterial) drugs inside.
In a mixture with norsulfazol, penicillin and ephedrine, streptocid is sometimes used for acute rhinitis; the powder is blown into the nasal cavity with the help of a special powder blower or is drawn into the nose during inhalation (see also Sunoref <<).
When taking a streptocide, headache, dizziness, nausea, vomiting are sometimes noted; cyanosis may develop.
Taking large amounts of the drug can cause changes in the hematopoietic system (leukopenia, agranulocytosis), sometimes in the nervous and cardiovascular systems (paresthesia, tachycardia), as well as dermatitis, diarrhea. Complications are rare in the urinary apparatus when taking streptocide.
Recently, instead of a streptocide, sulfadimezin, etazol, and other more effective sulfanilamide preparations, which cause fewer side effects, are increasingly being used.
Contraindications to treatment with streptocid are diseases of the hematopoietic system, nephrosis, nephritis, and basilial disease. With prolonged treatment with streptotsidom should periodically perform blood tests.
Method of issuance: powder; tablets of 0.3 and 0.5 g per pack of 10; 10% ointment; 5% liniment.
Storage of powder and tablets: List B. In a well-closed container.
Streptocid ointment (Unguentum Streptocidi). Contains 10 g of streptotsid and 90 g of vaseline (per 100 g of 10% ointment). Ointment white or light yellow.