Description of the medicine: Streptocidum (Streptocidum)

STREPTOCID (Streptocidum). Para-Aminobenzenesulfonamide.

Synonyms: Streptocidum white, Ambesid, Deseptyl, Dipron, Prontalbin, Prontalin, Prontoin, Prontosil album, Streptamin, Streptocidum album, Streptozol, Sulfamidyl, Sulfanilamide, Sulfanilamidum, Sulfanilamide and others.

White crystalline powder odorless. It is slightly soluble in water (1: 170), easily - in boiling water, it is difficult - in alcohol (1:35), soluble in solutions of caustic alkalis.

Has antimicrobial effect in relation to streptococci, meningococci, gonococcus, pneumococcus, Escherichia coli and some other bacteria.

When injected into the body streptotsid quickly absorbed. The highest concentration of the drug in the blood is created 1 to 2 hours after ingestion. After 4 hours, it is found in the cerebrospinal fluid. It is allocated mainly (90 - 95%) kidneys.

Apply streptocide for the treatment of angina, erysipelas, cystitis, pyelitis, enterocolitis, for the prevention and treatment of wound infection and other infectious diseases.

Assign adults to adults for 0.5 - 1, 0 g 5 - 6 times a day, only 3 - 6 g per day; Children under the age of 1 year - 0.05-0.1 g per reception for 2 to 5 years - 0.2-0.3 g, from 6 to 12 years - 0.3-0.5 g. With unconsciousness and vomiting, you can replace the purpose of the drug by inserting into the muscles, under the skin or into a vein of streptocid soluble.

Higher doses for adults inside: single 2 g, daily 7 g.

With superficial infectious diseases of the skin and mucous membranes of the nasal cavity and ear, with burns, ulcers, etc. Apply streptocide as an ointment (10%) or liniment (5%). At deep wounds, the streptocide is introduced into the cavity of the wound in the form of a carefully crushed sterilized powder (5 - 10 - 15 g); Simultaneously prescribe sulfanilamide (or other antibacterial) drugs inside.

In a mixture with norsulfazole, penicillin and ephedrine, streptocides are sometimes used for acute colds; The powder is injected into the nasal cavity by means of a special powder blower or drawn into the nose during inspiration (see also "Sunorreph" Ointment).

When taking streptocide sometimes there is a headache, dizziness, nausea, vomiting; Can develop cyanosis.

Taking large amounts of the drug can cause changes in the hematopoietic system (leukopenia, agranulocytosis), sometimes in the nervous and cardiovascular systems (paresthesia, tachycardia), as well as dermatitis, diarrhea. In the urinary apparatus, when streptocid is taken, complications are rare.

Recently, instead of streptocides, sulfadimezine, etazol and other more effective sulfanilamide preparations, which cause fewer side effects, are increasingly being used.

Contraindications to streptocid treatment are diseases of the hematopoietic system, nephrosis, nephritis, Graves' disease. With prolonged treatment with streptocid, blood tests should be performed periodically.

Form release: powder; Tablets of 0.3 and 0.5 g in a package of 10 pieces; 10% ointment; 5% liniment.

Storage of powder and tablets: List B. In a well ukuporennoy container.

Ointment streptotsidovaya (Unguentum Streptocidi). Contains 10 g of streptocide and 90 g of Vaseline (per 100 g of 10% ointment). Ointment is white or light yellow in color.