Medication Description: Sulfargin (Sulfarginum)
Silver salt of sulfazin (sulfadiazin).
Synonyms: Dermazin, Silverdin, Sulfadiazin silver, Flamazin, Dermazin, Flamazin, Silverdin, Sulfadiazine Silver, Sulfargin.
White with a creamy shade fine crystalline powder.
It differs from other sulfa drugs by the presence of a silver atom in the molecule, which enhances its local antimicrobial - bactericidal - action.
When applied topically as an ointment on the wound surfaces, there is a gradual release of silver ions, which ensures a long-lasting effect of the drug.
It is used as a 1% ointment called << Sulfargin >> ointment (Ugnuentum <Sulfarginum>). A uniform ointment of white or white with a creamy shade of color, with a characteristic odor.
Assign ointment <Sulfargin> topically to adults and children over 3 months for the prevention and treatment of purulent wounds and burns, trophic ulcers, bedsores. Used for the treatment of wound and burn surfaces in the 1st phase of the wound process with mild exudation; treatment of fresh burn surfaces (to prevent infection); for the treatment of superficial wounds and burns of I - III A degree in the 2nd and 3rd phases of the wound process, trophic ulcers, pressure sores, non-healing wounds, including stump wounds.
Ointment is applied to the affected surface (after surgical treatment and removal of necrotic tissue) with a thin layer (for dressing or open method). The dressing is changed 1 - 2 times a day or less. The maximum single dose of 3 g. The duration of treatment up to 3 weeks.
When using the ointment can develop skin-allergic reactions characteristic of sulfonamides, leukopenia. In rare cases, there are phenomena of short-term local irritation (burning, pain), which usually pass on their own in 5-10 minutes.
In the case of applying the ointment on a wide surface, the functional state of the kidneys, liver and the content of blood corpuscles should be monitored, patients are prescribed an abundant alkaline drink.
Ointment <Sulfargin> is contraindicated in premature babies, newborns and children up to 3 months; during pregnancy; patients with a pronounced deficiency of glucose - 6 - phosphate dehydrogenase and with increased sensitivity to sulfa drugs. Do not use the ointment for the treatment of deep purulent wounds and burn surfaces with abundant exudation.
Product form: 1% ointment in tubes of 50 and 180 g each and in glass jars of 500 g each.
Storage: List B. Banks - in the dark place, tubes - in normal conditions.
A similar ointment (cream) is produced abroad (Yugoslavia) under the name "Dermazin" (Dermasin) in tubes of 50 g each and in banks of 250 g each.