Description of the medicine: Sulfarginum (Sulfarginum)
Silver salt of sulfazine (sulfadiazine).
Synonyms: Dermazin, Silververdin, Silver sulfadiazine, Flamazin, Dermazin, Flamazin, Silverdin, Sulfadiazine Silver, Sulfargin.
Fine crystalline white with a creamy tint.
It differs from other sulfanilamide preparations by the presence of a silver atom in the molecule, which enhances its local antimicrobial - bactericidal - effect.
When applied topically in the form of an ointment to wound surfaces, a gradual release of silver ions occurs, which ensures the long-term effect of the drug.
It is used as a 1% ointment called ointment << Sulfargin >> (Ugnuentum <Sulfarginum>). A homogeneous ointment of a white or creamy-white color with a characteristic odor.
Prescribe ointment <Sulfargin> locally for adults and children older than 3 months for the prevention and treatment of purulent wounds and burns, trophic ulcers, bedsores. They are used to treat wound and burn surfaces in the 1st phase of the wound process with mild exudation; processing fresh burn surfaces (with the aim of preventing infection); for the treatment of superficial wounds and burns of I - III A degrees in the 2nd and 3rd phases of the wound process, trophic ulcers, pressure sores, non-healing wounds, including stump wounds.
The ointment is applied to the affected surface (after surgical treatment and removal of necrotic tissue) with a thin layer (under a bandage or open method). The dressing is changed 1 to 2 times a day or less. The maximum single dose, 3 g. The duration of treatment is up to 3 weeks.
When using the ointment, skin-allergic reactions characteristic of sulfa drugs, leukopenia can develop. In rare cases, short-term local irritant effects (burning, pain) are noted, which usually pass on their own after 5 - 10 minutes.
In the case of applying the ointment on a vast surface, the functional state of the kidneys, liver and the content of blood cells should be monitored, patients are prescribed a plentiful alkaline drink.
Ointment <Sulfargin> is contraindicated in premature babies, newborns and children up to 3 months; during pregnancy; patients with severe glucose - 6 - phosphate dehydrogenase deficiency and with increased sensitivity to sulfa drugs. Ointment should not be used to treat deep purulent wounds and burn surfaces with abundant exudation.
Release form: 1% ointment in tubes of 50 and 180 g and in glass jars of 500 g.
Storage: List B. Banks - in a dark place, tubes - in normal conditions.
A similar ointment (cream) is produced abroad (Yugoslavia) under the name "Dermasin" (Dermasin) in tubes of 50 g and banks of 250 g.