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Description medications: Sulfadimezin (Sulfadimezinum)
Sulfadimezin (Sulfadimezinum). 2- (p-Aminobenzolsulfamido) - 4, 6 - dimethylpyrimidine.
Synonyms: Diazil, Diazol, Dimethazil, Dimethyldebenal , Dimethylsulphadiazine, Dimethylsulphapyrimidine, Pirmazin, Sulfadimerazine, Sulfadimidine, Sulfadimidinum, Sulfamethazine, Sulfamezathil, Sulfamezathine, Sulmet, Sulphadimethylpyrimidine, Sulphadimidine, Superseptyl.
White or slightly yellow crystalline powder. Practically insoluble in water, easily soluble in acids and alkalis.
Apply with pneumococcal, streptococcal, meningococcal infections, sepsis, gonorrhea, and infections caused by E. coli and other microorganisms.
Sulfadimezin absorbed quickly, relatively low toxicity.
Doses for adults are the same as the dose norsulfazola.
Higher dose for adults inside single 2 g daily 7 g
Children designate 0.1 g / kg for the first reception, followed by 0.025 g / kg every 4 - 6 - 8 hours.
When treating dysentery sulfadimezin prescribed for adults as follows: in the 1st and 2nd days of the disease - 6 g per day (every 4 hours, 1 g); 3rd and 4th days - 4 g per day (every 6 hours, 1 g); the 5th and 6th days to 3 g per day (every 8 hours, 1 g). In the course of treatment from 25 to 30 grams of the drug. After the break, 5 - 6 days by a second treatment cycle in the 1st and 2nd days appoint 1 g in 4 hours (after 8 hours at night), only 5 grams per day; 3rd and 4th days - 1g every 4 hours (at night does not give), total 4 g per day; 5 th day - 1 g in 4 hours (at night does not give), total 3 g per day. Throughout the second cycle yield 21 g of product; with mild disease to reduce the dose can be 18 g.
Babies sulfadimezin prescribed for dysentery in the following doses up to 3 years - up to 0.2 g / kg per day; the daily dose is divided into 4 doses and given during the day without disturbing night's sleep. At this dose of medication taken for 7 days. Children over 4 years prescribed three times daily at a dose of 0.75 to 0.4 g depending on age.
Sulfadimezin as other sulfa drugs, often used in conjunction with antibiotics.
In combination with hloridinom sulfadimezin used for toxoplasmosis.
When treating sulfadimezinom designate a rich alkaline water. It is necessary to systematically produce a blood test, as well as in the treatment of other sulfanilamidnymi drugs.
Method of issuance: powder; Tablets of 0.25 and 0.5 g per pack of 10 pieces.
Storage: List B. The well-closed container, protected from light.
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