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Description of the medicine: Acephen (Acephenum)

ACEFEN (Acephenum). b-Dimethylaminoethyl ester of p-chlorophenoxyacetic acid hydrochloride.

Synonyms: Analux, Meclofenoxate, Centrophenoxin, Cerutil, Analux, Centrophenoxine, Cerutil, Claretil, Clofenoxine, Lucidril, Meclofenoxati hydrochloridum, Meclofenoxate hydrochloride, Meclon, Mexazine, Nisantol, Roxylyl, etc.

White crystalline powder. Easily soluble in water and alcohol.

Chemically different from typical nootropics, but, on the basis of pharmacological properties and therapeutic effects, is assigned to this group.

In the body, acefen breaks down, forming n-chlorophenoxyacetic acid and dimethylaminoethanol [OH - CH 2 - CH 2 - N (CH 3) 2]. This compound is an inhibitor of free radicals. It has independent significance as a mild CNS stimulant and nootropic agent. Available under the name "Deanol" (Deanol).

Synonyms: Dinetal, Etanamin, etc.

There are a number of derivatives of this compound possessing to one degree or another nootropic properties (demanol-aceglumate, or keregil, keregil; Demanoli aceglumas, Cleregil, Dardanin, Otrun, Risatarim, etc.). Acefen (meclofenoxate) is considered as one of the typical nootropics. It improves cognitive functions, has a moderate stimulating effect on the central nervous system, activates metabolic processes, improves synaptic transmission in the hypothalamic and other areas of the brain. Increases the content of acetylcholine in the synaptic endings and increases the density of cholinergic receptors.

It is used for asthenic (in hypochondriacal and asthenoipochondria states, for impaired mnemonic functions in the elderly and senile, for traumatic and vascular diseases of the brain), for obsessive neurosis and other neurotic conditions. In the clinic of nervous diseases, acefen is also used for diencephalic syndrome, cerebrovascular accident, and amyotrophic lateral syndrome.

Assign inside 0.1 to 0.3 g 3 to 5 times a day.

The course of treatment lasts 1 to 3 months. It can be prescribed in combination with other neurotropic drugs.

Acefen is usually well tolerated. In some cases, in patients with paranoid and hallucinatory symptoms, exacerbation of delusional and hallucinatory phenomena, the occurrence of fear and anxiety are possible. The drug is contraindicated in infectious diseases of the central nervous system.

Release form: tablets of 0.1 g, coated with a yellow shell, in a package of 50 pieces.

Storage: List B. In a dry, cool place.