Attention! Information is for reference only!
Before taking the course, consult a doctor!
WEB SITE ONLY DIRECTORY. NOT PHARMACY! We do not sell medicines! None!
0 1 2 3 4 5 6 7 8 A B C D E F G H I J K L M N O P Q R S T U V W X Y

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Description of the medicine: Nitroxoline (Nitroxolinum)

NITROXOLINE (Nitroxolinum). 5-Nitro-8-hydroxyquinoline.

Synonyms: 5-NOC (from the first letters of the chemical name for the compound "5-nitro-8-oxyquinol"), 5-NOK, Nibiol, Nikinol, Nikopet, Nitroxoline, Niuron, Noxibiol, Noxin, Uritrol and others.

A fine-grained powder of a yellow-green color. Almost nerastvorim in the water.

Has antibacterial effect on gram-positive and gram-negative bacteria; Is also effective against certain fungi (the genus Candida, etc.).

Unlike other derivatives of 8-hydroxyquinoline, 5-NOK is rapidly absorbed from the gastrointestinal tract and secreted unchanged by the kidneys, which is why a high concentration of the drug and urine is noted.

Applied with infections of the urinary tract (pyelonephritis, cystitis, urethritis, prostatitis, etc.), for the prevention of infections after operations on the kidney and urinary tract, as well as other diseases caused by sensitive to this drug microorganisms. It is often effective in the resistance of microflora to other antibacterial agents.

Assign inside. The average daily intake for adults is 0.4 g (0.1 g 4 times a day). The duration of treatment depends on the nature and severity of the disease. In most cases, the course of treatment is 2-3 weeks. If necessary, repeat courses with a two-week break. In severe cases, the daily dose is increased to 0.15 - 0.2 g 4 times a day.

The highest daily intake for adults is 0.8 g.

The average daily dose for children older than 5 years is 0.2-0.4 g (by 0.05-0.1 g 4 times a day), under 5 years - 0.2 g per day.

Duration of treatment 2 -3 weeks. In chronic infections of the urinary tract, the drug can be administered again for 2 weeks with a 2-week break.

For the prevention of infections in kidney and urinary tract surgery, 0.1 g per reception 4 times a day for 2 to 3 weeks is prescribed.

The drug is usually well tolerated. Sometimes there are diarrheal phenomena (nausea), so it is recommended to take it during meals. Allergic rash is possible.

With renal failure, caution should be exercised because of possible cumulation of the drug.

Urine in the treatment of the drug is painted in a saffron-yellow color.

With increased sensitivity to the derivatives of 8-hydroxyquinoline drug is contraindicated.

Product: tablets; Coated with an orange color, to 0.05 g (50 mg) in a package of 50 pieces.

Storage: List B. In a dry, sheltered from the world.