Description of the medicine: Pipemidic acid (Acidum pipemidiecum)
PIPEMIDIC ACID (Acidum pipemidiecum). 2-piperazine-5-oxo-8 ethyl-5, 8-dihydro-pyrido (2, 3-d) -pyrimidine-6-carboxylic acid.
Synonyms: Palin, Acipem, Balurol, Cistomid, Filtrax, Naril, Palin, Pimidel, Pipedae, Pipefort, Pipemidic acid, Pipram, Pipurin, Septidron, Solupemid, Uripan, Urisan, Urixin, Urodipin, Uromidin, Uropimid, dr.valid .
According to the chemical structure, it can be considered as a modified molecule of nalidixic acid.
A yellowish white powder, bitter in taste, darkening under the influence of light.
The drug has antibacterial activity. Active against Pseudomonas, which is associated with the presence of a piperazine nucleus in the molecule.
In clinical practice, pipemidic acid is especially effective in acute and chronic urinary tract infections.
Adults take orally 0.4 g (1 tablet 0.4 g or 2 capsules 0.2 g) 2 times a day (morning and evening). The course of treatment is 10 days or more, depending on the course of the disease.
Children from 1 year to 15 years are prescribed at the rate of 15 mg / kg, divided into 2 doses.
Women with relapses of infection are recommended to be administered simultaneously with an oral dose of 1 vaginal suppository daily for 7 to 10 days.
When using the drug, allergic skin reactions, nausea, pain in the stomach, photosensitivity phenomena are possible.
Contraindicated in pregnancy. Caution should be observed in renal failure. Children taking the drug should be under close medical supervision.
During treatment, it is recommended to maintain enhanced diuresis.
Method of release: in capsules of 0.1 and 0.2 g; tablets of 0.4 g; vaginal suppositories of 0.2 g; suspension (for children) in 100 ml vials containing 100 mg (0.1 g) in 5 ml.
Storage: List B. In the dark place.