Medication Description: Pipidic Acid (Acidum pipemidiecum)
PYPEMID ACID (Acidum pipemidiecum). 2-Piperazin-5-oxo-8 ethyl-5, 8-dihydropyrido (2, 3-d) -pyrimidine-6-carboxylic acid.
Synonyms: Palin, Acipem, Balurol, Cistomid, Filtrax, Naril, Palin, Pimidel, Pipedae, Pipefort, Pipemidic acid, Pipram, Pipurin, Septidron, Solupemid, Uripan, Urisan, Urixin, Urodipin, Uromidin, Uropidine, iridine, Iridan, Uripan, Urisan, Urodipin, Urodipin, Urodipin, Uropine .
According to the chemical structure, it can be considered as a modified nalidixic acid molecule.
A yellowish-white powder, bitter in taste, darkening under the influence of light.
The drug has antibacterial activity. It is active against Pseudomonas, which is associated with the presence of a piperazine nucleus in the molecule.
In clinical practice, pimemidium acid is especially effective in acute and chronic urinary tract infections.
Adults are taken orally at 0.4 g (1 tablet 0.4 g or 2 capsules of 0.2 g) 2 times a day (morning and evening). The course of treatment is 10 days or more, depending on the course of the disease.
Children from 1 year to 15 years are prescribed at the rate of 15 mg / kg, divided into 2 doses.
In case of recurrence of infection, it is recommended that women simultaneously with ingestion, prescribe 1 vaginal suppository daily for 7–10 days.
With the use of the drug may be allergic skin reactions, nausea, pain in the stomach, the phenomenon of photosensitivity.
Contraindicated in pregnancy. Caution should be exercised in case of renal failure. Children taking the drug should be under close medical supervision.
During treatment, it is recommended to maintain enhanced diuresis.
Method of production: in capsules of 0.1 and 0.2 g; tablets of 0.4 g; 0.2 g vaginal suppositories; suspension (for children) in bottles of 100 ml with a content of 100 mg (0.1 g) in 5 ml.
Storage: List B. In the dark spot.