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Description of the medicine: Pasomicinum

PASOMICINE (Pasomicinum).

Dihydrostreptomycin para-aminosalicylate. Salt PASK (3 moles) and dihydrostreptomycin (1 mole).

Synonyms: Dihydrostreptomycin-Pascat, Streptopas.

Powder or porous mass of white or yellowish color, bitter taste. Easily soluble in water, almost insoluble in alcohol. Easily destroyed in solutions of acids and alkalis and under the influence of light.

Applied for various forms of tuberculosis, nonspecific pneumonia, purulent processes caused by streptomycin-sensitive bacteria, as well as in the preoperative period, especially in persons with a history of tuberculosis. If necessary, pasomycin can be combined with other antibacterial drugs.

The resistance of microorganisms to pasomycin develops more slowly than to streptomycin and PASC.

Applied intramuscularly. The dose for adults is 1 g per day once. If the intramuscular injection is poorly tolerated, 0.5 g per day is administered with an additional intake of PASK (6 g) inside.

Children under 1 year are prescribed 0.1 g, from 1 to 3 years - 0.2-0.25 g, from 3 to 7 years - 0.25-0.3 g, from 7 to 12 years - 0.3-0.5 g per day.

A solution of pasomycin can also be administered to the fistula and pleural cavity (0.25-0.5 g).

Dissolve pasomycin in 2 - 3 ml of 0.25 - 0.5% solution of novocaine, isotonic sodium chloride solution or sterile water for injection. Use freshly prepared mortar.

With prolonged use of the drug, there may be disorders of the vestibular apparatus and a decrease in the severity of the hearing, skin itching, dermatitis, dizziness, nausea. Caution is needed when administering pasomycin for acute and chronic nephritis (due to possible delay in drug release) and inflammation of the auditory nerve. You can not prescribe pasomycin concomitantly with kanamycin, florimycin, monomycin, and other antibiotics that have otoi nephrotoxicity.

Form release: in hermetically sealed vials of 0.5 and 1 g (500 000 and 1 000 000 units), calculated on dihydrostreptomycin base (with the application of a solvent - 0.5% solution of novocaine in ampoules).

Storage: List B. In a dry, sheltered from the world.