Description of the medicine: Bonaphtonum (Bonaphtonum)
BONAFTON (Bonaphtonum). 6-Bromo-1, 2-naphthoquinone.
A reddish-orange crystalline powder. It is practically insoluble in water.
It has antiviral activity against the herpes simplex virus and some adenoviruses.
It is used to treat herpetic keratitis, viral skin diseases (herpes simplex, herpes zoster, condyloma, etc.), herpetic stomatitis, gingivitis, genital herpes, genital warts, and other viral diseases of the skin and mucous membranes of a viral nature.
In case of eye diseases, adults are taken orally (one hour after eating) 0.1 g 3-4 times a day; children - at 0.025 g from 1 to 4 times depending on age. At the same time, 0.05% ophthalmic ointment is laid over the eyelids 3-4 times a day.
With superficial herpetic keratitis and adenoviral keratoconjunctivitis, only eye ointment (0.05%) is prescribed 3-4 times a day for 7-10 days.
With simple and herpes zoster, they are taken orally by 0.1 g 3 to 5 times a day, and 0.5% ointment is applied to the lesions 2 to 3 times a day. In the genital area, 4 to 6 applications are made per day. Treatment is carried out with three 5-day cycles with 1 - 2-day breaks or two 10-day cycles with a 3 - 5-day break.
In children with skin diseases, 0.25% or 0.5% ointment is applied, which is applied to the lesions 3 to 4 times a day for 12 to 14 days or tablets are given orally at a dose of 0.025 g from 2 to 4 times a day depending on age.
For diseases of the oral mucosa, bonafton is prescribed orally 0.1 g 3–4 times a day (for 3–10–20 days) and locally in the form of 0.25% ointment 4–6 times a day (for 5– 10 minutes). With extensive erosion, 0.05% ointment is effective.
With topical application of bonafton, irritation phenomena occurring after discontinuation of the drug (ointment) are possible. When taken orally, in case of diarrhea or headache, the drug is canceled.
Method of release: tablets of 0.025 and 0.1 g, coated, soluble in the intestine, dark red; 0.05% eye ointment in tubes of 10 g; 0.25%, 0.5% and 1% ointment in tubes and glass jars for 30 g.
Storage: List B. Tablets - in a dark place; ointment under normal conditions.