Description of the medicine: Chloxylum (Chloxylum)
HLOXIL (Chloxylum). 1, 4-Bis- (trichloromethyl) benzene, or hexachloro-para-xylene.
White crystalline powder without taste or odor. It is practically insoluble in water, it is hardly soluble in alcohol.
Used for the treatment of liver helminthiases: opisthorchiasis, fascioliasis, clonorchosis.
The cycle of treatment with chloxyl lasts 2 days. 1 hour after a light breakfast (a glass of sweet tea, 100 g of white bread), the patient takes the drug inside in the form of a powder (in 1/2 cup of milk). The daily dose is 0.1 - 0.15 g / kg (6 - 10 g for an adult); take 2 g every 10 minutes. For 2 days, the patient receives 10 to 20 g of the drug.
There is evidence of the use of chloxyl in a 5-day regimen. The total dose per course is the same, but the patient receives daily 0.06 g / kg daily for 5 consecutive days.
A 3-day regimen is also proposed, according to which the drug is prescribed at 0.1 g / kg per day. The daily dose is given in 2 to 3 divided doses with an interval of 2 hours, washed down with milk. This scheme is recommended for mass use in foci of opisthorchiasis.
A laxative after administration of chloxyl is not prescribed.
If necessary, the treatment is repeated with an interval of at least 4 to 6 months.
With the use of chloxil, an increase in liver size, pain in the liver, proteinuria, changes in heart rate, pain and heart, increased eosinophilia are possible. Allergic phenomena may occur, probably due to the death and decay of the opisthorchis. When allergic reactions occur, antihistamines, calcium chloride are prescribed.
Contraindications: liver disease (not associated with helminthiasis), myocardial damage, pregnancy.
Insufficiently high efficiency, frequent side effects make it difficult to use chloxil for mass chemotherapy of trematodoses.
Release form: powder.
Storage: List B.