Description of the medicine: Chlorhexidine (Chlorhexidinum)
Chlorhexidine (Chlorhexidinum). 1, 6-Di- (para-chlorophenyl-guanido) -hexane.
Synonyms: Gibitan, Sebidin, Hibitan, Abacil, Biotensid, Chlorohex, Corsodyl, Fimeil, Hexadol, Hexol, Hibitane, Nolvasan, Plivasept, Rotersept, Sebidin, Septalone, Soretol, Sterilone, etc.
Available in the form of a bigluconate (Chlorhexidini bigluconas).
Chlorhexidine is one of the most active local antiseptic agents.
Chemically, it is a dichloro-containing derivative of biguanide. The structure is very close to bigumal (see).
Chlorhexidine has a fast and strong bactericidal effect on gram-positive and gram-negative bacteria. Does not affect viruses and spores.
The drug is stable and after processing the skin (hands, surgical field, etc.) it remains on it in a certain amount, which continues to give a bactericidal effect. The drug remains active in the presence of blood, pus, although somewhat reduced.
Chlorhexidine is also effective against pathogens of sexually transmitted diseases: treponem, gonococcus, trichomonas.
It is used to treat the surgical field and hands of the surgeon, sterilize surgical instruments, as well as for purulent-septic processes (washing surgical wounds, bladder, etc.) and for the prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis).
The drug is available in the form of a 20% aqueous solution. To treat the surgical field, a 20% solution of 70% ethyl alcohol is diluted in a ratio of 1:40. The resulting 0.5% aqueous-alcoholic solution of chlorhexidine bigluconate is treated with the surgical field 2 times with an interval of 2 minutes. To quickly sterilize instruments, use the same solution for 5 minutes.
To disinfect wounds, burns, use a 0.5% aqueous solution; for hand disinfection - 0.5% alcohol solution or 1% aqueous solution.
When using the drug to treat the surgeon's hands, transient dryness and itching of the skin, dermatitis are possible; stickiness of the skin of the hands is also possible for 3 to 5 minutes.
The drug is contraindicated in case of a tendency to allergic reactions and dermatitis. The simultaneous use of iodine preparations is undesirable in order to avoid the development of dermatitis. Do not use chlorhexidine solutions to treat the conjunctiva and to rinse the cavities.
A 0.1% aqueous solution of chlorhexidine bigluconate can also be used for general disinfection of rooms, sanitary equipment, etc.
Release form: 20% aqueous solution in bottles of 0.5; 3 and 5 liters.
Storage: in the dark place at room temperature.
For the individual prevention of sexually transmitted diseases, it is available in the form of a 0.05% solution in a special plastic package of 100 ml.
The drug Disteril, produced abroad, contains 1.5% of chlorhexidine bigluconate and 15% of benzalkonium (surface-active antiseptic), as well as a dye. The addition of benzalkonium enhances the disinfecting effect, and the dye allows you to accurately determine the area of the treated skin. It is used for processing the surgical field, disinfection of medical equipment.