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Description medications: Chlorhexidine (Chlorhexidinum)

Chlorhexidine (Chlorhexidinum). 1, 6-Di- (p-chlorophenyl-guanido) hexane.

Synonyms: Gibitan, Sebidin, Hibitan, Abacil, Biotensid, Chlorohex, Corsodyl , Fimeil, Hexadol, Hexol, Hibitane, Nolvasan, Plivasept, Rotersept, Sebidin, Septalone, Soretol, Sterilone and others.

Available in a bigluconate (Shlorhexidini bigluconas).

Chlorhexidine is one of the most active local antiseptic.

Chemically is dihlorsoderzhaschim biguanide derivatives. The structure is very close to bigumalyu (cm.).

Chlorhexidine has a rapid and strong bactericidal effect on gram-positive and gram-negative bacteria. It operates on viruses and spores.

The preparation is stable after treatment and skin them (hand operating field etc.) Stored therein in a quantity that extends to give bactericidal effect. The drug remains active in the presence of blood, pus, although somewhat reduced.

Chlorhexidine is also effective against pathogens of sexually transmitted diseases: treponemes, gonococci, trichomonas.

Applied for the treatment of the surgical field and hand surgeon, sterilization of surgical instruments, as well as septic processes (washing of surgical wounds, urinary bladder, and others.) And for the prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis).

The drug is available as a 20% aqueous solution. For the treatment of the surgical field is diluted to 20% solution of 70% ethyl alcohol in a ratio of 1:40. The resulting 0.5% hydroalcoholic solution is treated with chlorhexidine bigluconate operative field 2 times at intervals of 2 minutes. For rapid sterilization of instruments used in the same solution for 5 min.

For the disinfection of wounds, burns using 0.5% aqueous solution; for disinfecting hands - 0.5% alcohol solution or 1% aqueous solution.

When using the drug for the treatment of the surgeon's hands are possible transient dryness and itching of the skin, dermatitis; skin tackiness can also hand over 3 - 5 min.

The drug is contraindicated in the propensity to allergic reactions and dermatitis. It is undesirable to the simultaneous use of iodine preparations in order to prevent the development of dermatitis. Do not use solutions, chlorhexidine for the treatment of conjunctiva and rinsing the cavities.

0.1% aqueous solution of chlorhexidine bigluconate can also be used for general disinfection of premises, sanitary facilities, etc.

Product: 20% aqueous solution in vials of 0.5; 3 and 5 liters.

Storage: in the dark place at room temperature.

For individual prevention of sexually transmitted diseases is available as a 0.05% solution of the polymer in a special package of 100 ml.

Manufactured abroad preparation distearyl (Disteril) comprises 1, 5% chlorhexidine and 15% bigluconate benzalkonium (surfactant antiseptic) and dye. Adding disinfectant benzalkonium enhances the action, and the dye can accurately determine size is treated skin. It is used for the treatment of the surgical field, the disinfection of medical equipment.

Sibikort (Sibicort).